ArticleJournal of the International Society of Sports Nutrition2011
Potential therapeutic effects of branched-chain amino acids supplementation on resistance exercise-based muscle damage in humans.
Article in Journal of the International Society of Sports Nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression.Sports medicine - open · 2024Pooled it
- Pooled it
- Branched-Chain Amino Acids Supplementation Does Not Accelerate Recovery after a Change of Direction Sprinting Exercise Protocol.Nutrients · 2022Trial
- Effect of Branched-Chain Amino Acid Supplementation on Recovery Following Acute Eccentric Exercise.Nutrients · 2018Trial
- The effect of milk on the attenuation of exercise-induced muscle damage in males and females.European journal of applied physiology · 2015Trial
- Review
- The Role of the Gut Microbiome and Probiotics in Sports Performance: A Narrative Review Update.Nutrients · 2025Review
- Potential Influence of Exercise-Induced Rhabdomyolysis by Branched-Chain Amino Acid Supplementation.Iranian journal of public health · 2022Article
- Preventive and reparative effects of isoleucine against copper-induced oxidative damage in primary fish enterocytes.Fish physiology and biochemistry · 2017Article
- Treadmill Training with HAL Exoskeleton-A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy-Preliminary Study.Frontiers in neuroscience · 2017Article
- Reduced muscular fatigue after a 12-week leucine-rich amino acid supplementation combined with moderate training in elderly: a randomised, placebo-controlled, double-blind trial.BMJ open sport & exercise medicine · 2016Article
- Central and Peripheral Fatigue During Resistance Exercise - A Critical Review.Journal of human kinetics · 2015Article
- Muscle exercise in limb girdle muscular dystrophies: pitfall and advantages.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2015Review
- Acute effects of a commercially-available pre-workout supplement on markers of training: a double-blind study.Journal of the International Society of Sports Nutrition · 2014Article
- Exercise-induced muscle damage is reduced in resistance-trained males by branched chain amino acids: a randomized, double-blind, placebo controlled study.Journal of the International Society of Sports Nutrition · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Branched-chain amino acids (BCAA) supplementation has been considered an interesting nutritional strategy to improve skeletal muscle protein turnover in several conditions. In this context, there is evidence that resistance exercise (RE)-derived biochemical markers of muscle soreness (creatine kinase (CK), aldolase, myoglobin), soreness, and functional strength may be modulated by BCAA supplementation in order to favor of muscle adaptation. However, few studies have investigated such effects in well-controlled conditions in humans. Therefore, the aim of this short report is to describe the potential therapeutic effects of BCAA supplementation on RE-based muscle damage in humans. The main point is that BCAA supplementation may decrease some biochemical markers related with muscle soreness but this does not necessarily reflect on muscle functionality.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.