ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2012
Clostridium difficile prevalence rates in a large healthcare system stratified according to patient population, age, gender, and specimen consistency.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Inhibition of Quinolone- and Multi-Drug-Resistant Clostridioides Difficile Strains by Multi Strain Synbiotics-An Option for Diarrhea Management in Nursing Facilities.International journal of environmental research and public health · 2021Article
- Epidemiology and outcome of Clostridium difficile infections in patients hospitalized in Internal Medicine: findings from the nationwide FADOI-PRACTICE study.BMC infectious diseases · 2016Observational
- Rapid change of fecal microbiome and disappearance of Clostridium difficile in a colonized infant after transition from breast milk to cow milk.Microbiome · 2016Article
- Recurrence and death after Clostridium difficile infection: gender-dependant influence of proton pump inhibitor therapy.SpringerPlus · 2016Article
- Impact of Clostridium difficile infection among pneumonia and urinary tract infection hospitalizations: an analysis of the Nationwide Inpatient Sample.BMC infectious diseases · 2015Article
- Clostridium difficile carriage in hospitalized cancer patients: a prospective investigation in eastern China.BMC infectious diseases · 2014Article
- Learning Data-Driven Patient Risk Stratification Models for Clostridium difficile.Open forum infectious diseases · 2014Article
- Ribotype 027 Clostridium difficile infections with measurable stool toxin have increased lactoferrin and are associated with a higher mortality.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014Article
- Real-time cellular analysis coupled with a specimen enrichment accurately detects and quantifies Clostridium difficile toxins in stool.Journal of clinical microbiology · 2014Article
- Reducing inappropriate antibiotic prescribing in the residential care setting: current perspectives.Clinical interventions in aging · 2014Review
- Elevated lactoferrin is associated with moderate to severe Clostridium difficile disease, stool toxin, and 027 infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013Article
- Is fidaxomicin worth the cost? An economic analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Article
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10 authors.
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Abstract
We evaluated Clostridium difficile prevalence rates in 2,807 clinically indicated stool specimens stratified by inpatient (IP), nursing home patient (NH), outpatient (OP), age, gender, and specimen consistency using bacterial culture, toxin detection, and polymerase chain reaction (PCR) ribotyping. Rates were determined based on the detection of toxigenic C. difficile isolates. We identified significant differences in the rates between patient populations and with age. Specimens from NH had a higher rate (46%) for toxigenic C. difficile than specimens from IP (18%) and OP (17%). There were no gender-related differences in the rates. Liquid specimens had a lower rate (15%) than partially formed and soft specimens (25%) and formed specimens (18%) for the isolation of toxigenic C. difficile. The nontoxigenic rate was lowest for NH (4%) and highest for patients<20 years of age (23%). We identified 31 different toxigenic ribotypes from a sampling of 190 isolates that showed the lowest diversity in NH. Fluoroquinolone resistance was observed in 93% of the 027 isolates, all of the 053 isolates, and in four other ribotypes. We observed different rates for toxigenic C. difficile in stratified patient populations, with the highest rate for NH, a low overall nontoxigenic rate, and fluoroquinolone resistance.
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