ArticleResearch in gerontological nursing2012
Prevalence of comorbidity and its association with traumatic brain injury and outcomes in older adults.
Article in Research in gerontological nursing, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Severe traumatic brain injury and long-term survival: a meta-analysis on life expectancy and mortality trends.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- Long-term life expectancy in severe traumatic brain injury: a systematic review.European journal of physical and rehabilitation medicine · 2024Pooled it
- Comorbidity in traumatic brain injury and functional outcomes: a systematic review.European journal of physical and rehabilitation medicine · 2021Pooled it
- Comorbidity in adults with traumatic brain injury and all-cause mortality: a systematic review.BMJ open · 2019Pooled it
- Effects of Transport to Trauma Centers on Survival Outcomes Among Severe Trauma Patients in Korea: Nationwide Age-Stratified Analysis.Journal of Korean medical science · 2024Article
- The impact of age and intensity of treatment on the outcome of traumatic brain injury.Frontiers in neurology · 2024Article
- Care patterns and predictors of community residence among older patients after hospital discharge for traumatic brain injury.Journal of the American Geriatrics Society · 2023Article
- Mild traumatic brain injury-induced persistent blood-brain barrier disruption is prevented by cyclosporine A treatment in hypertension.Frontiers in neurology · 2023Article
- Moderate and severe traumatic brain injury in general hospitals: a ten-year population-based retrospective cohort study in central Norway.Scandinavian journal of trauma, resuscitation and emergency medicine · 2022Article
- Successful Community Discharge Among Older Adults With Traumatic Brain Injury Admitted to Inpatient Rehabilitation Facilities.Archives of rehabilitation research and clinical translation · 2022Article
- White matter degradation near cerebral microbleeds is associated with cognitive change after mild traumatic brain injury.Neurobiology of aging · 2022Article
- Brain age estimation reveals older adults' accelerated senescence after traumatic brain injury.GeroScience · 2022Article
- Age Moderates the Effect of Injury Severity on Functional Trajectories in Traumatic Brain Injury: A Study Using the NIDILRR Traumatic Brain Injury Model Systems National Dataset.Journal of clinical medicine · 2022Article
- Functional motor improvement during inpatient rehabilitation among older adults with traumatic brain injury.PM & R : the journal of injury, function, and rehabilitation · 2022Article
- The Association between Skull Bone Fractures and the Mortality Outcomes of Patients with Traumatic Brain Injury.Emergency medicine international · 2022Article
- Application of multiple testing procedures for identifying relevant comorbidities, from a large set, in traumatic brain injury for research applications utilizing big health-administrative data.Frontiers in big data · 2022Article
- Article
- Acute cognitive impairment after traumatic brain injury predicts the occurrence of brain atrophy patterns similar to those observed in Alzheimer's disease.GeroScience · 2021Article
- The risk of pulmonary tuberculosis after traumatic brain injury.Scientific reports · 2021Article
- Oculomotor Deficits and Symptom Severity Are Associated With Poorer Dynamic Mobility in Chronic Mild Traumatic Brain Injury.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The study aims were to examine the association between age, comorbidity, and cause of injury in older adults with traumatic brain injury (TBI); and to determine which comorbidities relate to mortality, length of stay, and functional outcome at hospital discharge, controlling for initial injury severity, age, and sex. A retrospective cohort study design was used; clinical and outcome trauma registry data were obtained for 196 adults 55 and older with TBI. The majority had at least one comorbid condition (e.g., hypertension, alcohol abuse). In-hospital mortality was 31%. Among the oldest-old, motor vehicle collisions and falls were significantly associated with specific chronic diseases. Prior myocardial infarction was significantly associated with an increased risk of in-hospital death. Injury Severity Score and Glasgow Coma Scale score were predictive of discharge function, but comorbidity did not add significantly to the model. Primary TBI prevention efforts in older adults must consider the impact of comorbidity and cause of injury, particularly in the oldest-old. Alcohol abuse is common in older adults with TBI; screening should be conducted and interventions developed to prevent future injury. Future study is warranted to understand the interplay between pathophysiology of comorbid disease and injury and how to best manage rehabilitation within the context of aging.
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Registered trials
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