ArticleInternational journal of hypertension2012
Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents: Influences of Endothelin-1 Gene and Chronic Stress Exposure.
Article in International journal of hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Impact of 12-Month Smartphone Breathing Meditation Program upon Systolic Blood Pressure among Non-Medicated Stage 1 Hypertensive Adults.International journal of environmental research and public health · 2020Trial
- A randomized controlled pilot trial of classroom-based mindfulness meditation compared to an active control condition in sixth-grade children.Journal of school psychology · 2014Trial
- Meditation smartphone application effects on prehypertensive adults' blood pressure: Dose-response feasibility trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018Article
- Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants.JCI insight · 2017Article
- Formative evaluation on cultural tailoring breathing awareness meditation smartphone apps to reduce stress and blood pressure.mHealth · 2017Article
- Evaluation of an mHealth Medication Regimen Self-Management Program for African American and Hispanic Uncontrolled Hypertensives.Journal of personalized medicine · 2015Article
- "It takes a village" to raise research productivity: Impact of a Trauma Interdisciplinary Group for Research (TIGR) at an urban, Level 1 trauma center.The journal of trauma and acute care surgery · 2013Article
- Interactive influences of ethnicity, endothelin-1 gene, and everyday discrimination upon nocturnal ambulatory blood pressure.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2013Article
- Tension Tamer: delivering meditation with objective heart rate acquisition for adherence monitoring using a smart phone platform.Journal of alternative and complementary medicine (New York, N.Y.) · 2013Article
- Mindfulness-based interventions for physical conditions: a narrative review evaluating levels of evidence.ISRN psychiatry · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Stress-activated gene × environment interactions may contribute to individual variability in blood pressure reductions from behavioral interventions. We investigated effects of endothelin-1 (ET-1) LYS198ASN SNP and discriminatory stress exposure upon impact of 12-week behavioral interventions upon ambulatory BP (ABP) among 162 prehypertensive African American adolescents. Following genotyping, completion of questionnaire battery, and 24-hour ABP monitoring, participants were randomized to health education control (HEC), life skills training (LST), or breathing awareness meditation (BAM). Postintervention ABP was obtained. Significant three-way interactions on ABP changes indicated that among ET-1 SNP carriers, the only group to show reductions was BAM from low chronic stress environments. Among ET-1 SNP noncarriers, under low chronic stress exposure, all approaches worked, especially BAM. Among high stress exposure noncarriers, only BAM resulted in reductions. If these preliminary findings are replicated via ancillary analyses of archival databases and then via efficacy trials, selection of behavioral prescriptions for prehypertensives will be edging closer to being guided by individual's underlying genetic and environmental factors incorporating the healthcare model of personalized preventive medicine.
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Registered trials
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