ArticleInternational journal of pediatrics2012
Advances in the management of meconium aspiration syndrome.
Article in International journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- The Care of Preterm and Term Newborns with Respiratory Conditions: A Systematic Synthesis of Evidence from Low- and Middle-Income Countries.Neonatology · 2025Pooled it
- Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2016Pooled it
- Fetal inflammatory response severity on placental histology identifies neonates at risk for meconium aspiration syndrome.Pediatric research · 2026Article
- Article
- Assessment of Vitality, Blood Profile, and Degree of Meconium Staining on the Skin in Newborn Dogs According to Its Birth Weight.Veterinary sciences · 2023Article
- Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study.Children (Basel, Switzerland) · 2023Article
- Clinical characteristics of meconium aspiration syndrome in neonates with different gestational ages and the risk factors for neurological injury and death: A 9-year cohort study.Frontiers in pediatrics · 2023Article
- Meconium Aspiration Syndrome in Animal Models: Inflammatory Process, Apoptosis, and Surfactant Inactivation.Animals : an open access journal from MDPI · 2022Review
- Use of off-label compounded oral sildenafil in the management of persistent pulmonary hypertension of the newborn: A case report.Journal of cardiovascular and thoracic research · 2022Article
- Approach to the Connection between Meconium Consistency and Adverse Neonatal Outcomes: A Retrospective Clinical Review and Prospective In Vitro Study.Children (Basel, Switzerland) · 2021Article
- Evidence of both foetal inflammation and hypoxia-ischaemia is associated with meconium aspiration syndrome.Scientific reports · 2021Article
- Meconium Aspiration Syndrome: A Narrative Review.Children (Basel, Switzerland) · 2021Review
- Determinants of Neonatal Sepsis among Neonates Admitted to Public Hospitals in Central Ethiopia: Unmatched Case-control Study.Global pediatric health · 2021Article
- [Clinical features and prognosis of meconium aspiration syndrome complicated by pulmonary hemorrhage in neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019Article
- Article
- Activation of Toll-like receptors in meconium aspiration syndrome.Journal of perinatology : official journal of the California Perinatal Association · 2018Observational
- Meconium exposure and autism risk.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- The effect of meconium exposure on the expression and differentiation of amniotic fluid mesenchymal stem cells.Journal of neonatal-perinatal medicine · 2017Article
- Lung ultrasonography to diagnose meconium aspiration syndrome of the newborn.The Journal of international medical research · 2016Observational
- [Clinical effect of high-frequency oscillatory ventilation combined with pulmonary surfactant in treatment of neonatal severe meconium aspiration syndrome complicated by pulmonary hemorrhage].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meconium aspiration syndrome (MAS) is a common cause of severe respiratory distress in term infants, with an associated highly variable morbidity and mortality. MAS results from aspiration of meconium during intrauterine gasping or during the first few breaths. The pathophysiology of MAS is multifactorial and includes acute airway obstruction, surfactant dysfunction or inactivation, chemical pneumonitis with release of vasoconstrictive and inflammatory mediators, and persistent pulmonary hypertension of newborn (PPHN). This disorder can be life threatening, often complicated by respiratory failure, pulmonary air leaks, and PPHN. Approaches to the prevention of MAS have changed over time with collaboration between obstetricians and pediatricians forming the foundations for care. The use of surfactant and inhaled nitric oxide (iNO) has led to the decreased mortality and the need for extracorporeal membrane oxygenation (ECMO) use. In this paper, we review the current understanding of the pathophysiology and management of MAS.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.