ArticleSensors (Basel, Switzerland)2011
Enzyme-polymers conjugated to quantum-dots for sensing applications.
Article in Sensors (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 38 citations in OpenAlex.
- The Effect of Capping Agents on Gold Nanostar Stability, Functionalization, and Colorimetric Biosensing Capability.Nanomaterials (Basel, Switzerland) · 2022Article
- Antimicrobial activity of silver sulfide quantum dots functionalized with highly conjugated Schiff bases in a one-step synthesis.RSC advances · 2022Article
- Stimuli-Responsive Systems in Optical Humidity-Detection Devices.Materials (Basel, Switzerland) · 2019Article
- Biocompatible Fluorescent Core-Shell Nanoconjugates Based on Chitosan/Bi2S3 Quantum Dots.Nanoscale research letters · 2016Article
- Cytotoxicity investigation of luminescent nanohybrids based on chitosan and carboxymethyl chitosan conjugated with BiToxicology research · 2016Article
- Metabolic tumor profiling with pH, oxygen, and glucose chemosensors on a quantum dot scaffold.Inorganic chemistry · 2014Article
- One-step colloidal synthesis of biocompatible water-soluble ZnS quantum dot/chitosan nanoconjugates.Nanoscale research letters · 2013Article
- Investigating bioconjugation by atomic force microscopy.Journal of nanobiotechnology · 2013Review
- One-step biofunctionalization of quantum dots with chitosan and N-palmitoyl chitosan for potential biomedical applications.Molecules (Basel, Switzerland) · 2013Article
- Surface biofunctionalized CdS and ZnS quantum dot nanoconjugates for nanomedicine and oncology: to be or not to be nanotoxic?International journal of nanomedicineArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present research, the concept of developing a novel system based on polymer-enzyme macromolecules was tested by coupling carboxylic acid functionalized poly(vinyl alcohol) (PVA-COOH) to glucose oxidase (GOx) followed by the bioconjugation with CdS quantum-dots (QD). The resulting organic-inorganic nanohybrids were characterized by UV-visible spectroscopy, infrared spectroscopy, Photoluminescence spectroscopy (PL) and transmission electron microscopy (TEM). The spectroscopy results have clearly shown that the polymer-enzyme macromolecules (PVA-COOH/GOx) were synthesized by the proposed zero-length linker route. Moreover, they have performed as successful capping agents for the nucleation and constrained growth of CdS quantum-dots via aqueous colloidal chemistry. The TEM images associated with the optical absorption results have indicated the formation of CdS nanocrystals with estimated diameters of about 3.0 nm. The "blue-shift" in the visible absorption spectra and the PL values have provided strong evidence that the fluorescent CdS nanoparticles were produced in the quantum-size confinement regime. Finally, the hybrid system was biochemically assayed by injecting the glucose substrate and detecting the formation of peroxide with the enzyme horseradish peroxidase (HRP). Thus, the polymer-enzyme-QD hybrid has behaved as a nanostructured sensor for glucose detecting.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.