Evidence map›Paper›PMID 22163413›Full record

ReviewSensors (Basel, Switzerland)2010

Biomedical use of isothermal microcalorimeters.

Olivier Braissant, Dieter Wirz, Beat Göpfert, A U Daniels

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Again and Again-Survival ofPharmaceutics · 2024
    Article
  4. Article
  5. Bioenergetics of aerobic and anaerobic growth ofFrontiers in microbiology · 2023
    Article
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  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olivier BraissantLaboratory of Biomechanics & Biocalorimetry, Biozentrum/Pharmazentrum, University of Basel, Klingelbergstrasse 50-70, 4056 Basel, Switzerland. olivier.braissant@unibas.ch
Dieter Wirz
Beat Göpfert
A U Daniels

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isothermal microcalorimetry is becoming widely used for monitoring biological activities in vitro. Microcalorimeters are now able to measure heat production rates of less than a microwatt. As a result, metabolism and growth of relatively small numbers of cultured bacteria, protozoans, human cells and even small animals can be monitored continuously and extremely accurately at any chosen temperature. Dynamic effects on these organisms of changes in the culture environment--or of additions to it--are easily assessed over periods from hours to days. In addition microcalorimetry is a non-destructive method that does not require much sample preparation. It is also completely passive and thus allows subsequent evaluations of any kind on the undisturbed sample. In this review, we present a basic description of current microcalorimetry instruments and an overview of their use for various biomedical applications. These include detecting infections, evaluating effects of pharmaceutical or antimicrobial agents on cells, monitoring growth of cells harvested for tissue eingineering, and assessing medical and surgical device material physico-chemical stability and cellular biocompatibility.

Indexed as

AnimalsCalorimetryEnvironmental MonitoringHumansTemperatureantimicrobial agent testingbacteriahuman cell linesmaterials biocompatibilitymicrocalorimeters

Identifiers

PMID22163413
PMCPMC3230962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.