Evidence map›Paper›PMID 22163335›Full record

ReviewViruses2011

Antiviral immunity in amphibians.

Guangchun Chen, Jacques Robert

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Quantity - but not diversity - of secreted peptides and proteins increases with age in the tree frogThe journal of venomous animals and toxins including tropical diseases · 2021
    Article
  10. Review
  11. Article
  12. Review
  13. Chinese Giant Salamander (International journal of molecular sciences · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Guangchun ChenDepartment of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Jacques RobertDepartment of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
University of Rochester Medical Center · US

Funding

PHS HHS 2 R24 AL 059830-06
6 · The paper itself

Abstract

Although a variety of virus species can infect amphibians, diseases caused by ranaviruses ([RVs]; Iridoviridae) have become prominent, and are a major concern for biodiversity, agriculture and international trade. The relatively recent and rapid increase in prevalence of RV infections, the wide range of host species infected by RVs, the variability in host resistance among population of the same species and among different developmental stages, all suggest an important involvement of the amphibian immune system. Nevertheless, the roles of the immune system in the etiology of viral diseases in amphibians are still poorly investigated. We review here the current knowledge of antiviral immunity in amphibians, focusing on model species such as the frog Xenopus and the salamander (Ambystoma tigrinum), and on recent progress in generating tools to better understand how host immune defenses control RV infections, pathogenicity, and transmission.

Indexed as

Amphibian ProteinsAmphibiansAnimalsCaudataDNA Virus InfectionsHumansRanavirusXenopus laevisAmphibian Proteinsamphibianiridovirusviral infection

Identifiers

PMID22163335
PMCPMC3230842
OpenAlexW2098534337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.