Evidence map›Paper›PMID 22163260›Full record

ReviewDeutsches Arzteblatt international2011

Intraductal papillary mucinous neoplasia (IPMN) of the pancreas: its diagnosis, treatment, and prognosis.

Robert Grützmann, Stefan Post, Hans Detlev Saeger, Marco Niedergethmann

Abstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. [Painful, livid indurations on both lower legs].Dermatologie (Heidelberg, Germany) · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Intra-Ampullary Papillary-Tubular Neoplasm: A Population-Based Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  12. [Early stage pancreatic cancer].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018
    Review
  13. Observational
  14. Analysis of clinical characteristics and treatment of pancreatic cystic tumors.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2016
    Article
  15. Article
  16. Review
  17. Review
  18. IPMN: surgical treatment.Langenbeck's archives of surgery · 2013
    Review
  19. Article
  20. The incidental cystic pancreas mass: a practical approach.Cancer imaging : the official publication of the International Cancer Imaging Society · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Robert GrützmannChirurgische Klinik, Universitätsmedizin Mannheim, Med. Fakultät Mannheim, Mannheim, Germany.
Stefan Post
Hans Detlev Saeger
Marco Niedergethmann
University Hospital Heidelberg · DEUniversity Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe many varieties of cystic pancreatic tumor, and especially intraductal papillary mucinous neoplasia (IPMN), have attracted increased attention recently. Their incidence may be rising, and their histopathological evaluation and classification have become more precise than before.

methodsWe discuss the current diagnostic evaluation of IPMN, along with treatment and prognostication, on the basis of the current international guideline as well as pertinent literature retrieved by a selective PubMed search.

resultsThe preoperative diagnostic evaluation of IPMN is often problematic. In particular, it may not be possible to differentiate main-duct disease from branch-duct disease (MD-IPMN vs. BD-IPMN) before surgery--a distinction with implications for prognosis and treatment, as MD-IPMN is more often malignant. An IPMN adenoma can develop into invasive pancreatic cancer. Because firm diagnostic criteria are still lacking, it is recommended that all MD-IPMN lesions and all large BD-IPMN lesions should be resected. Partial pancreatectomy with clean margins is the treatment of choice.

conclusionAs IPMN seems to be a slow-growing precursor of pancreatic cancer, it is possible that its early detection and surgical treatment can lead to a cure. No conclusion about the efficacy of surveillance and follow-up programs can be drawn from the available evidence. A better understanding of the natural course of IPMN and the biology of pancreatic cancer is needed to enable further improvements in diagnosis and treatment.

Indexed as

Adenocarcinoma, MucinousHumansPancreatectomyPancreatic NeoplasmsPapilloma, IntraductalPrognosisTreatment Outcome

Identifiers

PMID22163260
PMCPMC3230826
OpenAlexW1574558206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.