Evidence map›Paper›PMID 22162954›Full record

ArticlePLoS medicine2011

Measuring the population burden of injuries--implications for global and national estimates: a multi-centre prospective UK longitudinal study.

Ronan A Lyons, Denise Kendrick, Elizabeth M Towner, Nicola Christie, Steven Macey, Carol Coupland, Belinda J Gabbe, UK Burden of Injuries Study Group

Registry-linked trialAbstract readComparative StudyMulticenter Study
In one paragraph

Article in PLoS medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03413189 (PREDICTABLE), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03413189 unknown statusnot on this mapstarted 2018, after this paper: background citation

PREDICTABLE: The Effect of Exercise Dosage on Physical Function, Cognition and Disability Following Critical Illness

TypeobservationalSponsorAustralian and New Zealand Intensive Care Research CentreRan2018 to 2023Enrolled40ConditionsCritical IllnessArmsReview of medical records, Assessment of physical and cognitive function, Interview of patients, carers and/or family members
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Impact of primary trauma care (PTC) training on post-trauma recovery: a pre-post intervention study of health-related outcomes in Vietnam.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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  5. Health-related quality of life 12 years after injury: prevalence and predictors of outcomes in a cohort of injured Māori.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ronan A LyonsCentre for Health Information Research and Evaluation, College of Medicine, Swansea University, UK. r.a.lyons@swansea.ac.uk
Denise Kendrick
Elizabeth M Towner
Nicola Christie
Steven Macey
Carol Coupland
Belinda J Gabbe
UK Burden of Injuries Study Group

Funding

Department of Health 0010009
6 · The paper itself

Abstract

backgroundCurrent methods of measuring the population burden of injuries rely on many assumptions and limited data available to the global burden of diseases (GBD) studies. The aim of this study was to compare the population burden of injuries using different approaches from the UK Burden of Injury (UKBOI) and GBD studies. METHODS AND

findingsThe UKBOI was a prospective cohort of 1,517 injured individuals that collected patient-reported outcomes. Extrapolated outcome data were combined with multiple sources of morbidity and mortality data to derive population metrics of the burden of injury in the UK. Participants were injured patients recruited from hospitals in four UK cities and towns: Swansea, Nottingham, Bristol, and Guildford, between September 2005 and April 2007. Patient-reported changes in quality of life using the EQ-5D at baseline, 1, 4, and 12 months after injury provided disability weights used to calculate the years lived with disability (YLDs) component of disability adjusted life years (DALYs). DALYs were calculated for the UK and extrapolated to global estimates using both UKBOI and GBD disability weights. Estimated numbers (and rates per 100,000) for UK population extrapolations were 750,999 (1,240) for hospital admissions, 7,982,947 (13,339) for emergency department (ED) attendances, and 22,185 (36.8) for injury-related deaths in 2005. Nonadmitted ED-treated injuries accounted for 67% of YLDs. Estimates for UK DALYs amounted to 1,771,486 (82% due to YLDs), compared with 669,822 (52% due to YLDs) using the GBD approach. Extrapolating patient-derived disability weights to GBD estimates would increase injury-related DALYs 2.6-fold.

conclusionsThe use of disability weights derived from patient experiences combined with additional morbidity data on ED-treated patients and inpatients suggests that the absolute burden of injury is higher than previously estimated. These findings have substantial implications for improving measurement of the national and global burden of injury.

Indexed as

Disability EvaluationQuality-Adjusted Life YearsAdolescentAdultAgedCitiesCohort StudiesEmergency Medical ServicesEnglandFemaleHospitalizationHumansLongitudinal StudiesMaleMiddle AgedProspective Studies

Identifiers

PMID22162954
PMCPMC3232198

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.