ArticleInternational journal of general medicine2011
Seroprevalence of IgG anti-Toxocara species antibodies in a population of patients with suspected allergy.
Article in International journal of general medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Stage-specific gene expression profiling ofOpen veterinary journal · 2026Article
- Seroprevalence of toxocariasis among allergic patients in Kuwait and its association with eosinophilia.Parasite epidemiology and control · 2022Article
- Allergic asthma manifestations in human and seropositivity toFrontiers in medicine · 2022Article
- Toxocara Awareness Among Medical Practitioners in Saudi Arabia.EcoHealth · 2021Article
- A new ELISA and western blot technique based on recombinant TES antigen and/or larval antigen for the detection of toxocariasis in humans.Parasitology · 2021Article
- Urticaria and silent parasitism by Ascaridoidea: Component-resolved diagnosis reinforces the significance of this association.PLoS neglected tropical diseases · 2020Article
- Seroprevalence of ToxocaraCanis in Asthmatic Children and its Relation to the Severity of Diseases - a Case-Control Study.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2018Article
- A case of atopic dermatitis caused byClinical and molecular allergy : CMA · 2018Article
- A case of apparent contact dermatitis caused by Toxocara infection.Case reports in dermatological medicine · 2014Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundToxocara canis is an intestinal nematode affecting dogs and cats, which causes human infection when embryonated eggs excreted in dog feces are ingested. Humans are paratenic hosts. Although the larvae do not develop into adult worms in the human body, they may migrate to various tissues and organs where they can survive for several years, giving rise to several clinical symptoms, which can present in allergy-like form.
methodsOver 5 years, we examined 9985 patients referred for suspected allergies, based on symptoms such as dermatitis, urticaria, rhinitis, asthma, and conjunctivitis; 753 patients who had allergy tests negative or unrelated to clinical history were tested for seropositivity to T. canis by enzyme-linked immunosorbent assay (ELISA) or Western blotting (WB).
resultsIn 240 patients (31.8%), ELISA or WB or both tests were positive for T. canis immunoglobulin G (IgG) antibodies: in particular, 64 of them (26.7%) were positive to ELISA, 110 (45.8%) to WB, and 66 (27.5%) to both tests. Asthma was the most common clinical presentation. Two thirds of patients underwent subsequent anthelmintic therapy and showed a complete remission of symptoms and, in 43% of patients retested by ELISA and WB, became negative to Toxocara.
conclusionThese findings strongly suggest that T. canis plays a significant role in inducing chronic symptoms presenting as suspected allergies.
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