ArticleJournal of allergy2012
Environmental effects on fractional exhaled nitric oxide in allergic children.
Article in Journal of allergy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- The association of exhaled nitric oxide with air pollutants in young infants of asthmatic mothers.Environmental health : a global access science source · 2023Trial
- The effects of facemasks on airway inflammation and endothelial dysfunction in healthy young adults: a double-blind, randomized, controlled crossover study.Particle and fibre toxicology · 2018Trial
- A cross-sectional analysis of medical conditions and environmental factors associated with fractional exhaled nitric oxide (FeNO) in women and children from the ISA birth cohort, Costa Rica.Environmental research · 2023Article
- Longitudinal hierarchical Bayesian models of covariate effects on airway and alveolar nitric oxide.Scientific reports · 2023Article
- Long-term exposures to air pollutants affectThe European respiratory journal · 2021Article
- Hierarchical Bayesian estimation of covariate effects on airway and alveolar nitric oxide.Scientific reports · 2021Article
- Assessing the Respiratory Effects of Air Pollution from Biomass Cookstoves on Pregnant Women in Rural India.International journal of environmental research and public health · 2020Article
- Fractional Exhaled Nitric Oxide (FENO) in the management of asthma: a position paper of the Italian Respiratory Society (SIP/IRS) and Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC).Multidisciplinary respiratory medicine · 2020Article
- A Panel Study on Lung Function and Bronchial Inflammation among Children Exposed to Ambient SO₂ from an Oil Refinery.International journal of environmental research and public health · 2019Article
- Genetic and epigenetic susceptibility of airway inflammation to PMEnvironmental health : a global access science source · 2017Article
- Traffic-related air pollution and alveolar nitric oxide in southern California children.The European respiratory journal · 2016Article
- Longitudinal effects of air pollution on exhaled nitric oxide: the Children's Health Study.Occupational and environmental medicine · 2014Article
- The value of FeNO measurement in childhood asthma: uncertainties and perspectives.Multidisciplinary respiratory medicine · 2013Article
- Noninvasive effects measurements for air pollution human studies: methods, analysis, and implications.Journal of exposure science & environmental epidemiologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fractional exhaled nitric oxide (FeNO) is a non-invasive marker of airway inflammation in asthma and respiratory allergy. Environmental factors, especially indoor and outdoor air quality, may play an important role in triggering acute exacerbations of respiratory symptoms. The authors have reviewed the literature reporting effects of outdoor and indoor pollutants on FeNO in children. Although the findings are not consistent, urban and industrial pollution-mainly particles (PM(2.5) and PM(10)), nitrogen dioxide (NO(2)), and sulfur dioxide (SO(2))-as well as formaldehyde and electric baseboard heating have been shown to increase FeNO, whilst ozone (O(3)) tends to decrease it. Among children exposed to Environmental Tobacco Smoke (ETS) with a genetic polymorphisms in nitric oxide synthase genes (NOS), a higher nicotine exposure was associated with lower FeNO levels. Finally, although more studies are needed in order to better investigate the effect of gene and environment interactions which may affect the interpretation of FeNO values in the management of children with asthma, clinicians are recommended to consider environmental exposures when taking medical histories for asthma and respiratory allergy. Further research is also needed to assess the effects of remedial interventions aimed at reducing/abating environmental exposures in asthmatic/allergic patients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.