Fatal infusion reactions to cetuximab: role of immunoglobulin e-mediated anaphylaxis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. The role of IgE specific for galactose-α-1,3-galactose in predicting cetuximab induced hypersensitivity reaction: a systematic review and a diagnostic meta-analysis.Scientific reports · 2020
   Pooled it
2. Clinical usefulness of anti-α3Gal immunoglobulin E assays for cetuximab-mediated anaphylaxis in head and neck cancer.Immuno-oncology technology · 2025
   Article
3. Clinical evidence of immunogenicity of CAR-T cell therapies and its implication in the clinical development of CAR-T drug products.Frontiers in immunology · 2025
   Review
4. Targeting lung cancer with clinically relevant EGFR mutations using anti-EGFR RNA aptamer.Molecular therapy. Nucleic acids · 2023
   Article
5. Simplifying the detection and monitoring of protein glycosylation during in vitro glycoengineering.Scientific reports · 2023
   Article
6. Nationwide pharmacovigilance data for cetuximab-induced anaphylaxis and predictive model validation using prospective specific IgE detection.The World Allergy Organization journal · 2021
   Article
7. Recombinant Proteins and Monoclonal Antibodies.Advances in biochemical engineering/biotechnology · 2021
   Review
8. Environmental and Molecular Drivers of the α-Gal Syndrome.Frontiers in immunology · 2019
   Review
9. Outpatient Emergencies: Anaphylaxis.The Medical clinics of North America · 2017
   Review
10. Utility of serum anti-cetuximab immunoglobulin E levels to identify patients at a high risk of severe hypersensitivity reaction to cetuximab.British journal of clinical pharmacology · 2017
    Article
11. Tick-induced allergies: mammalian meat allergy, tick anaphylaxis and their significance.Asia Pacific allergy · 2015
    Review
12. Drug allergens and food--the cetuximab and galactose-α-1,3-galactose story.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2014
    Review
13. Case Report About Fatal or Near-Fatal Hypersensitivity Reactions to Cetuximab: Anticetuximab IgE as a Valuable Screening Test.Clinical Medicine Insights. Oncology · 2014
    Article
14. Emerging antigens involved in allergic responses.Current opinion in immunology · 2013
    Review
15. Tick bites and red meat allergy.Current opinion in allergy and clinical immunology · 2013
    Review
16. Delayed anaphylaxis to red meat in patients with IgE specific for galactose alpha-1,3-galactose (alpha-gal).Current allergy and asthma reports · 2013
    Review
17. Relationship between red meat allergy and sensitization to gelatin and galactose-α-1,3-galactose.The Journal of allergy and clinical immunology · 2012
    Article
18. Clinical spectrum of α-Gal syndrome: from immediate-type to delayed immediate-type reactions to mammalian innards and meat.Allergo journal international
    Review
19. Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression.mAbs
    Article

Corrections and comments

• Comment on
  Fatal infusion reaction to cetuximab: the need for predictive risk factors and safer patient selection.2011

Authors and funding

5 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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