ArticleJournal of clinical microbiology2012
Emergence and continuous evolution of genotype 1E rubella viruses in China.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Human Riboviruses: A Comprehensive Study.Journal of molecular evolution · 2025Review
- Prevalence of preconception TORCH infections and its influential factors: evidence from over 2 million women with fertility desire in southern China.BMC women's health · 2023Article
- Design of a chimaeric antigen and its use in the detection of IgG antibodies against rubella virus.Virology journal · 2022Article
- Importation and circulation of rubella virus lineages 1E-L2 and 2B-L2c between 2018 and 2021 in China: Virus evolution and spatial-temporal transmission characteristics.Virus evolution · 2022Article
- Phylogenetic reconstruction of the initial stages of the spread of the SARS-CoV-2 virus in the Eurasian and American continents by analyzing genomic data.Virus research · 2021Article
- Phylogeography of rubella virus in Asia: Vaccination and demography shape synchronous outbreaks.Epidemics · 2019Article
- Seroprevalence of Maternal and Cord Antibodies Specific for Diphtheria, Tetanus, Pertussis, Measles, Mumps and Rubella in Shunyi, Beijing.Scientific reports · 2018Article
- Rubella seroprevalence among pregnant women in Beijing, China.BMC infectious diseases · 2018Article
- Genetic diversity of currently circulating rubella viruses: a need to define more precise viral groups.The Journal of general virology · 2017Article
- Molecular Epidemiology of Rubella Virus Strains Detected Around the Time of the 2012-2013 Epidemic in Japan.Frontiers in microbiology · 2017Article
- Analysis of complete genomes of the rubella virus genotypes 1E and 2B which circulated in China, 2000-2013.Scientific reports · 2016Article
- Vaccination in secondary school students expedites rubella control and prevents congenital rubella syndrome.BMC infectious diseases · 2016Article
- Genomic characterization of a persistent rubella virus from a case of Fuch' uveitis syndrome in a 73 year old man.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2015Article
- Evolutionary analysis of rubella viruses in mainland China during 2010-2012: endemic circulation of genotype 1E and introductions of genotype 2B.Scientific reports · 2015Article
- Article
- Phylogenetic analysis of rubella viruses identified in Uganda, 2003-2012.Journal of medical virology · 2014Article
- The influence of secondary structure, selection and recombination on rubella virus nucleotide substitution rate estimates.Virology journal · 2014Article
- Molecular evolutionary and epidemiological dynamics of genotypes 1G and 2B of rubella virus.PloS one · 2014Article
- Rubella epidemic caused by genotype 1E rubella viruses in Beijing, China, in 2007-2011.Virology journal · 2013Article
- Molecular evolution of hemagglutinin (H) gene in measles virus genotypes D3, D5, D9, and H1.PloS one · 2012Article
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Authors and funding
36 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In China, rubella vaccination was introduced into the national immunization program in 2008, and a rubella epidemic occurred in the same year. In order to know whether changes in the genotypic distribution of rubella viruses have occurred in the postvaccination era, we investigate in detail the epidemiological profile of rubella in China and estimate the evolutionary rate, molecular clock phylogeny, and demographic history of the predominant rubella virus genotypes circulating in China using Bayesian Markov chain Monte Carlo phylodynamic analyses. 1E was found to be the predominant rubella virus genotype since its initial isolation in China in 2001, and no genotypic shift has occurred since then. The results suggest that the global 1E genotype may have diverged in 1995 and that it has evolved at a mutation rate of 1.65 × 10(-3) per site per year. The Chinese 1E rubella virus isolates were grouped into either cluster 1 or cluster 2, which likely originated in 1997 and 2006, respectively. Cluster 1 viruses were found in all provinces examined in this study and had a mutation rate of 1.90 × 10(-3) per site per year. The effective number of infections remained constant until 2007, and along with the introduction of rubella vaccine into the national immunization program, although the circulation of cluster 1 viruses has not been interrupted, some viral lineages have disappeared, and the epidemic started a decline that led to a decrease in the effective population size. Cluster 2 viruses were found only in Hainan Province, likely because of importation.
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