Evidence map›Paper›PMID 22162307›Full record

ArticleAngewandte Chemie (International ed. in English)2012

Reactive and bioactive cationic α-helical polypeptide template for nonviral gene delivery.

Nathan P Gabrielson, Hua Lu, Lichen Yin, Dong Li, Fei Wang, Jianjun Cheng

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Synthesis of polypeptides via bioinspired polymerization of in situ purifiedProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  10. Review
  11. Article
  12. Review
  13. Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Helical antimicrobial polypeptides with radial amphiphilicity.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathan P GabrielsonDepartment of Materials Science and Engineering, University of Illinois, Urbana-Champaign, 1304 W. Green Street, Urbana, IL 61801, USA.
Hua Lu
Lichen Yin
Dong Li
Fei Wang
Jianjun Cheng

Funding

Stem cell fate and embryonic developmentR01GM083812 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI WANG, FEI · 2007 to 2014
$2.4M
Developing Clinically Applicable, Cancer-Targeting Polymeric NanoconjugatesDP2OD007246 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2010 to 2010
$2.4M
Development of Helical Polypeptides for Non-Viral Gene Delivery SystemsR21EB013379 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2011 to 2012
$415k
Development of Functional Poly(alpha-hydroxy acids) for Drug Delivery ApplicationR21EB009486 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2009 to 2010
$406k
Camptothecin-Containing Nanoparticles: Control Over Particle Size, BiodistributioR21CA152627 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2011 to 2012
$334k
NCI NIH HHS R21 CA152627NIBIB NIH HHS 1R21EB009486NIBIB NIH HHS R21 EB009486NIBIB NIH HHS R21 EB013379NIGMS NIH HHS GM083812NIH HHS 1DP2OD007246NIH HHS DP2 OD007246PHS HHS 1R21A152627
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Transfer TechniquesAnimalsCationsChlorocebus aethiopsCOS CellsGenetic TherapyGenetic VectorsHumansMolecular StructurePeptidesProtein Structure, SecondaryCationsPeptides

Identifiers

PMID22162307
PMCPMC3555134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.