Evidence map›Paper›PMID 22161338›Full record

ArticleAdvances in experimental medicine and biology2012

A systems-biology approach to yeast actin cables.

Tyler Drake, Eddy Yusuf, Dimitrios Vavylonis

Open access · greenAbstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Tyler DrakeDepartment of Physics, Lehigh University, Bethlehem, PA 18015, USA. tyler.gates.drake@gmail.com
Eddy Yusuf
Dimitrios Vavylonis
Lehigh University · USSurya University · ID

Funding

Computational Analysis and Modeling of Contractile Ring AssemblyR21GM083928 · NIGMS · LEHIGH UNIVERSITY · PI HUANG, SHARON XIAOLEI, VAVYLONIS, DIMITRIOS · 2008 to 2009
$386k
NIGMS NIH HHS R21 GM083928NIGMS NIH HHS R21GM083928
6 · The paper itself

Abstract

We focus on actin cables in yeast as a model system for understanding cytoskeletal organization and the workings of actin itself. In particular, we highlight quantitative approaches on the kinetics of actin-cable assembly and methods of measuring their morphology by image analysis. Actin cables described by these studies can span greater lengths than a thousand end-to-end actin-monomers. Because of this difference in length scales, control of the actin-cable system constitutes a junction between short-range interactions - among actin-monomers and nucleating, polymerization-facilitating, side-binding, severing, and cross-linking proteins - and the emergence of cell-scale physical form as embodied by the actin cables themselves.

Indexed as

ActinsCell Cycle ProteinsCytoplasmFungal ProteinsKineticsModels, BiologicalProtein MultimerizationSaccharomyces cerevisiaeSchizosaccharomycesSignal TransductionSpecies SpecificitySystems BiologyYeastsActinsCell Cycle ProteinsFungal Proteins

Identifiers

PMID22161338
PMCPMC3241217
OpenAlexW1932930368

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.