ArticlePharmaceutical research2012
Magnetorelaxometry assisting biomedical applications of magnetic nanoparticles.
Article in Pharmaceutical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 139 citations in OpenAlex.
- Article
- Parameter Estimation and Quantification of Magnetic Nanoparticles Based on Improved Particle Swarm Optimization.Micromachines · 2025Article
- Versatile and Accessible Magnetic Diagnosis Platform with Different Types of Magnetic Particles for Liquid and Solid Biopsies.International journal of molecular sciences · 2023Article
- Monitoring magnetic nanoparticle clustering and immobilization with thermal noise magnetometry using optically pumped magnetometers.Nanoscale advances · 2023Article
- In vivo Biodistribution and Clearance of Magnetic Iron Oxide Nanoparticles for Medical Applications.International journal of nanomedicine · 2023Review
- Experimental demonstration of improved magnetorelaxometry imaging performance using optimized coil configurations.Medical physics · 2022Article
- Optical Microscopy Systems for the Detection of Unlabeled Nanoparticles.International journal of nanomedicine · 2022Review
- Article
- Model-based optimized steering and focusing of local magnetic particle concentrations for targeted drug delivery.Drug delivery · 2021Article
- 2D Quantitative Imaging of Magnetic Nanoparticles by an AC Biosusceptometry Based Scanning Approach and Inverse Problem.Sensors (Basel, Switzerland) · 2021Article
- MNP-Enhanced Microwave Medical Imaging by Means of Pseudo-Noise Sensing.Sensors (Basel, Switzerland) · 2021Article
- Microfluidic Synthesis, Control, and Sensing of Magnetic Nanoparticles: A Review.Micromachines · 2021Review
- Advanced analysis of magnetic nanoflower measurements to leverage their use in biomedicine.Nanoscale advances · 2021Article
- Pulsed Optically Pumped Magnetometers: Addressing Dead Time and Bandwidth for the Unshielded Magnetorelaxometry of Magnetic Nanoparticles.Sensors (Basel, Switzerland) · 2021Article
- Simultaneous Coercivity and Size Determination of Magnetic Nanoparticles.Sensors (Basel, Switzerland) · 2020Article
- Quantitative 2D Magnetorelaxometry Imaging of Magnetic Nanoparticles using Optically Pumped Magnetometers.Sensors (Basel, Switzerland) · 2020Article
- Intracellular Quantification and Localization of Label-Free Iron Oxide Nanoparticles by Holotomographic Microscopy.Nanotechnology, science and applications · 2020Article
- Fabrication of paper-based enzyme immobilized microarray by 3D-printing technique for screening α-glucosidase inhibitors in mulberry leaves and lotus leaves.Chinese medicine · 2019Article
- Magnetorelaxometry in the Presence of a DC Bias Field of Ferromagnetic Nanoparticles Bearing a Viscoelastic Corona.Sensors (Basel, Switzerland) · 2018Article
- Screening for ovarian cancer: imaging challenges and opportunities for improvement.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to their biocompatibility and small size, iron oxide magnetic nanoparticles (MNP) can be guided to virtually every biological environment. MNP are susceptible to external magnetic fields and can thus be used for transport of drugs and genes, for heat generation in magnetic hyperthermia or for contrast enhancement in magnetic resonance imaging of biological tissue. At the same time, their magnetic properties allow one to develop sensitive and specific measurement methods to non-invasively detect MNP, to quantify MNP distribution in tissue and to determine their binding state. In this article, we review the application of magnetorelaxometry (MRX) for MNP detection. The underlying physical properties of MNP responsible for the generation of the MRX signal with its characteristic parameters of relaxation amplitude and relaxation time are described. Existing single and multi-channel MRX devices are reviewed. Finally, we thoroughly describe some applications of MRX to cellular MNP quantification, MNP organ distribution and MNP-based binding assays. Providing specific MNP signals, a detection limit down to a few nanogram MNP, in-vivo capability in conscious animals and measurement times of a few seconds, MRX is a valuable tool to improve the application of MNP for diagnostic and therapeutic purposes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.