Trial reportJournal of behavioral medicine2012
Therapeutic mechanisms of a mindfulness-based treatment for IBS: effects on visceral sensitivity, catastrophizing, and affective processing of pain sensations.
Trial report in Journal of behavioral medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 93 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identifying the Neurofunctional Connections Supporting Mindfulness Meditation Based Analgesia
Smartphone Stress Management Training for Irritable Bowel Syndrome
Who cites it
93 citing papers in PubMed, 3 syntheses or guidelines pooled it, 209 citations in OpenAlex.
- A systematic review of associations between functional connectivity, mood and cognition in patients with irritable bowel syndrome.Brain imaging and behavior · 2026Pooled it
- A systematic review and meta-analysis of mindfulness- and acceptance-based interventions for affect intolerance/sensitivity.Behaviour research and therapy · 2020Pooled it
- Emotion regulation in patients with somatic symptom and related disorders: A systematic review.PloS one · 2019Pooled it
- The role of endogenous opioids in mindfulness and sham mindfulness-meditation for the direct alleviation of evoked chronic low back pain: a randomized clinical trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Trial
- Moderators and Nonspecific Predictors of Treatment Benefits in a Randomized Trial of Mindfulness-Based Stress Reduction vs Cognitive-Behavioral Therapy vs Usual Care for Chronic Low Back Pain.The journal of pain · 2023Trial
- Trial
- Mediators and moderators of change in mindfulness-based stress reduction for painful diabetic peripheral neuropathy.Journal of behavioral medicine · 2020Trial
- Effects of Mindfulness-Oriented Recovery Enhancement Versus Social Support on Negative Affective Interference During Inhibitory Control Among Opioid-Treated Chronic Pain Patients: A Pilot Mechanistic Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2019Trial
- Psychological mechanisms driving stress resilience in mindfulness training: A randomized controlled trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2019Trial
- Randomized Controlled Trial of Brief Mindfulness Training and Hypnotic Suggestion for Acute Pain Relief in the Hospital Setting.Journal of general internal medicine · 2017Trial
- Mindfulness Meditation-Based Pain Relief Employs Different Neural Mechanisms Than Placebo and Sham Mindfulness Meditation-Induced Analgesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Trial
- Mindfulness and cognitive-behavioral interventions for chronic pain: differential effects on daily pain reactivity and stress reactivity.Journal of consulting and clinical psychology · 2015Trial
- Mindfulness-oriented recovery enhancement for chronic pain and prescription opioid misuse: results from an early-stage randomized controlled trial.Journal of consulting and clinical psychology · 2014Trial
- The Role of Heart Rate Variability in Mindfulness-Based Pain Relief.The journal of painTrial
- Psychological Predictors of Response to Open-Label Versus Double-Blind Placebo in a Randomized Controlled Trial in Irritable Bowel Syndrome.Psychosomatic medicineTrial
- A Patient-Centered Ethical Framework for Irritable Bowel Syndrome Care: Communication, Trust, Nutrition-Sensitive Care, and Self-Management.Nutrients · 2026Review
- Nondual Awareness as a Novel Chronic Pain Relieving Mechanism.Psychology of consciousness (Washington, D.C.) · 2026Article
- Brain Changes Underlying Irritable Bowel Syndrome Symptom Improvement in Response to Mindfulness-Based Stress Reduction.Neurogastroenterology and motility · 2026Article
- The sustained effect of 5-week EmotionCore mindfulness training on emotion regulation and emotional intelligence: heterogeneous benefits for depression and anxiety across subgroups.Frontiers in psychiatry · 2025Article
- Contemporaneous Link Between Pain and Craving in Patients Recovering from Prescription Opioid Use Disorder During Residential Treatment.Substance use & misuse · 2025Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Irritable bowel syndrome (IBS) is a prevalent functional disorder characterized by abdominal pain and hypervigilance to gastrointestinal sensations. We hypothesized that mindfulness training (MT), which promotes nonreactive awareness of emotional and sensory experience, may target underlying mechanisms of IBS including affective pain processing and catastrophic appraisals of gastrointestinal sensations. Seventy five female IBS patients were randomly assigned to participate in either 8 weeks of MT or a social support group. A theoretically grounded, multivariate path model tested therapeutic mediators of the effect of MT on IBS severity and quality of life. Results suggest that MT exerts significant therapeutic effects on IBS symptoms by promoting nonreactivity to gut-focused anxiety and catastrophic appraisals of the significance of abdominal sensations coupled with a refocusing of attention onto interoceptive data with less emotional interference. Hence, MT appears to target and ameliorate the underlying pathogenic mechanisms of IBS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.