Evidence map›Paper›PMID 22160441›Full record

Trial reportJournal of youth and adolescence2012

Internalizing symptoms: effects of a preventive intervention on developmental pathways from early adolescence to young adulthood.

Linda Trudeau, Richard Spoth, G Kevin Randall, W Alex Mason, Chungyeol Shin

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of youth and adolescence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Reducing Internalizing Symptoms Among High-Risk, Hispanic Adolescents: Mediators of a Preventive Family Intervention.Prevention science : the official journal of the Society for Prevention Research · 2016
    Trial
  4. Trial
  5. Trial
  6. Efficacy of a Latino mother-child communication intervention in elementary schools.The Journal of school nursing : the official publication of the National Association of School Nurses · 2015
    Trial
  7. Annual Research Review: Beyond the target - understanding crossover effects in family-centered prevention.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Beyond effectiveness of the Strengthening Families Program (10-14): a scoping RE-AIM-based review.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2021
    Article
  12. Two-Year Impact of Prevention Programs on Adolescent Depression: an Integrative Data Analysis Approach.Prevention science : the official journal of the Society for Prevention Research · 2018
    Article
  13. Preventing Youth Internalizing Symptoms Through the Familias Unidas Intervention: Examining Variation in Response.Prevention science : the official journal of the Society for Prevention Research · 2018
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Preventing internalizing symptoms among Hispanic adolescents: a synthesis across Familias Unidas trials.Prevention science : the official journal of the Society for Prevention Research · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linda TrudeauPartnerships in Prevention Science Institute, Iowa State University, ISU Research Park, Building 2, Suite 2400, 2625 North Loop Drive, Ames, IA 50010, USA. ltrudeau@iastate.edu
Richard Spoth
G Kevin Randall
W Alex Mason
Chungyeol Shin

Funding

Rural Family and Community Drug Abuse Prevention ProjectR01AA014702 · NIAAA · IOWA STATE UNIVERSITY · PI SPOTH, RICHARD · 2003 to 2007
$3.0M
RURAL FAMILY AND COMMUNITY DRUG ABUSE PREVENTION PROJECTR01DA007029 · NIDA · IOWA STATE UNIVERSITY · PI SPOTH, RICHARD L · 1991 to 2001
$969k
RURAL YOUTH AT RISK: EXTENSION-BASED PREVENTION EFFICACYR01MH049217 · NIMH · IOWA STATE UNIVERSITY · PI SPOTH, RICHARD L · 1992 to 2000
$248k
NIAAA NIH HHS AA 014702NIAAA NIH HHS R01 AA014702NIDA NIH HHS DA 007029NIMH NIH HHS MH 49217
6 · The paper itself

Abstract

This study examined the mediated and moderated effects of a universal family-focused preventive intervention, delivered during young adolescence, on internalizing symptoms assessed in young adulthood. Sixth grade students (N=446; 52% female; 98% White) and their families from 22 rural Midwestern school districts were randomly assigned to the experimental conditions in 1993. Self-report questionnaires were administered at seven time points (pre-test to young adulthood-age 21) to those receiving the Iowa Strengthening Families Program (ISFP) and to the control group. Results showed that growth factors of adolescent internalizing symptoms (grades 6-12) were predicted by ISFP condition and risk status (defined as early substance initiation). Moderation of the condition effect by risk status was found, with higher-risk adolescents benefitting more from the ISFP. Results also supported the hypothesis that the ISFP's effect on internalizing symptoms in young adulthood was mediated through growth factors of adolescents' internalizing symptoms; risk moderation, however, was only marginally significant in young adulthood. The relative reduction rate on clinical or subclinical levels of young adult internalizing symptoms was 28%, indicating that for every 100 young adults displaying clinical or subclinical levels of internalizing symptoms from school districts not offering an intervention, there could be as few as 72 displaying those levels of symptoms in school districts that offered middle school prevention programming. These findings highlight how the positive effects of family-focused universal interventions can extend to non-targeted outcomes and the related potential public-health impact of scaling up these interventions.

Indexed as

Family TherapyAdolescentAdolescent DevelopmentAnxietyChildDepressionFemaleFollow-Up StudiesHumansInternal-External ControlMaleModels, PsychologicalModels, StatisticalPsychological TestsRiskSelf Report

Identifiers

PMID22160441
PMCPMC3771682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.