Suggested pathway to assess radiation safety of 11C-labeled PET tracers for first-in-human studies.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Utility of Preclinical Dosimetry for First-in-Human Studies with PET Drugs Labeled with Common Radionuclides: A Systematic Review of Radiation Dose Estimates.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
   Pooled it
2. [(11)C]TASP457, a novel PET ligand for histamine H3 receptors in human brain.European journal of nuclear medicine and molecular imaging · 2016
   Trial
3. Biodistribution and dosimetry of the carbon-11 labelled PARP1-selective PET radiopharmaceutical [EJNMMI research · 2026
   Article
4. CXCR4-targeted PET imaging of glioblastoma using [EJNMMI radiopharmacy and chemistry · 2026
   Article
5. Radiation dosimetry of [EJNMMI research · 2025
   Article
6. Good Manufacturing Practice Validation and Radiation Dosimetry for the Clinical Application of a Novel α7-nAChR Radioligand: [Molecules (Basel, Switzerland) · 2025
   Article
7. Whole-Body PET Imaging in Humans Shows ThatJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
   Article
8. Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [European journal of nuclear medicine and molecular imaging · 2022
   Article
9. Modulation of Secondary Cancer Risks from Radiation Exposure by Sex, Age and Gonadal Hormone Status: Progress, Opportunities and Challenges.Journal of personalized medicine · 2022
   Review
10. Target occupancy study and whole-body dosimetry with a MAGL PET ligand [EJNMMI research · 2022
    Article
11. Radiation Absorbed Dose to the Embryo and Fetus from Radiopharmaceuticals.Seminars in nuclear medicine · 2022
    Review
12. Human biodistribution and dosimetry of [EJNMMI physics · 2021
    Article
13. Biodistribution and radiation dosimetry of the positron emission tomography probe for AMPA receptor, [Scientific reports · 2021
    Article
14. [European journal of nuclear medicine and molecular imaging · 2019
    Article
15. Human biodistribution and radiation dosimetry of the 5-HTEJNMMI research · 2019
    Article
16. Characterization of [Molecular imaging and biology · 2019
    Article
17. Comparison of two PET radioligands, [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2017
    Article
18. Synthesis and preliminary PET imaging ofNature communications · 2017
    Article
19. Radiation Dosimetry of a Novel Adenosine AMolecular imaging and biology · 2017
    Article
20. 11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2017
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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