ReviewPlant cell reports2012
From miracle fruit to transgenic tomato: mass production of the taste-modifying protein miraculin in transgenic plants.
Review in Plant cell reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Complexity Meets Risk-The Next Generation of Genome-Edited Plants Challenges Established Concepts for Environmental Risk Assessment in the EU.Plants (Basel, Switzerland) · 2025Review
- Miracle Fruit, a Potential Taste-modifier to Improve Food Preferences: A Review.Current nutrition reports · 2024Review
- Improvement of recombinant miraculin production in transgenic tomato by crossbreeding-based genetic background modification.Transgenic research · 2022Article
- Environmental risk assessment of transgenic miraculin-accumulating tomato in a confined field trial in Japan.Plant biotechnology (Tokyo, Japan) · 2021Article
- The Chromosome-Level Genome of Miracle Fruit (Frontiers in plant science · 2021Article
- Miracle Berry as a Potential Supplement in the Control of Metabolic Risk Factors in Cancer.Antioxidants (Basel, Switzerland) · 2020Review
- Comparison of thePlant biotechnology (Tokyo, Japan) · 2018Article
- High-level production of single chain monellin mutants with enhanced sweetness and stability in tobacco chloroplasts.Planta · 2018Article
- Exposure of kale root to NaCl and NaScientific reports · 2018Article
- Molecular Breeding to Create Optimized Crops: From Genetic Manipulation to Potential Applications in Plant Factories.Frontiers in plant science · 2016Review
- Novel promoters that induce specific transgene expression during the green to ripening stages of tomato fruit development.Plant cell reports · 2012Article
- Plant molecular pharming 2012 and beyond.Plant cell reports · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The utility of plants as biofactories has progressed in recent years. Some recombinant plant-derived pharmaceutical products have already reached the marketplace. However, with the exception of drugs and vaccines, a strong effort has not yet been made to bring recombinant products to market, as cost-effectiveness is critically important for commercialization. Sweet-tasting proteins and taste-modifying proteins have a great deal of potential in industry as substitutes for sugars and as artificial sweeteners. The taste-modifying protein, miraculin, functions to change the perception of a sour taste to a sweet one. This taste-modifying function can potentially be used not only as a low-calorie sweetener but also as a new seasoning that could be the basis of a new dietary lifestyle. However, miraculin is far from inexpensive, and its potential as a marketable product has not yet been fully developed. For the last several years, biotechnological production of this taste-modifying protein has progressed extensively. In this review, the characteristics of miraculin and recent advances in its production using transgenic plants are summarized, focusing on such topics as the suitability of plant species as expression hosts, the cultivation method for transgenic plants, the method of purifying miraculin and future advances required to achieve industrial use.
Indexed as
Identifiers
22160133What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.