Evidence map›Paper›PMID 22159917›Full record

ArticleOrganic & biomolecular chemistry2012

Water-soluble, deep-red fluorescent squaraine rotaxanes.

Erin L Cole, Easwaran Arunkumar, Shuzhang Xiao, Bryan A Smith, Bradley D Smith

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. New photosensitizers for photodynamic therapy.The Biochemical journal · 2016
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erin L ColeDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
Easwaran Arunkumar
Shuzhang Xiao
Bryan A Smith
Bradley D Smith

Funding

PROMOTERS AND INHIBITORS OF MEMBRANE FUSIONR01GM059078 · NIGMS · UNIVERSITY OF NOTRE DAME · PI SMITH, BRADLEY D · 1999 to 2019
$5.8M
Chemistry-Biochemistry-Biology Training Program at Notre DameT32GM075762 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F, MOBASHERY, SHAHRIAR · 2007 to 2021
$3.7M
Superior Near-IR Dyes for BioimagingR43EB009266 · NIBIB · MOLECULAR TARGETING TECHNOLOGIES, INC. · PI GRAY, BRIAN DAVID · 2009 to 2009
$177k
NIBIB NIH HHS R43 EB009266NIBIB NIH HHS R43-EB009266NIGMS NIH HHS R01 GM059078NIGMS NIH HHS T32 GM075762NIGMS NIH HHS T32GM075762
6 · The paper itself

Abstract

Eight fluorescent squaraine rotaxanes with deep-red absorption/emission wavelengths were prepared and assessed for chemical stability and suitability as water-soluble, fluorescent tracers. The most stable squaraine rotaxanes have four large stopper groups attached to the ends of the encapsulated squaraine, and two members of this structural class have promise as highly fluorescent tracers with rapid renal clearance and very low tissue uptake in living mice.

Indexed as

AbsorptionAnimalsBiological TransportCyclobutanesFluorescent DyesMiceModels, MolecularMolecular ConformationPhenolsRotaxanesSolubilityWaterCyclobutanesFluorescent DyesPhenolsRotaxanessquaraineWater

Identifiers

PMID22159917
PMCPMC4015105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.