Evidence map›Paper›PMID 22158429›Full record

ReviewNature reviews. Microbiology2011

Candida albicans morphogenesis and host defence: discriminating invasion from colonization.

Neil A R Gow, Frank L van de Veerdonk, Alistair J P Brown, Mihai G Netea

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 448 papers.

0numbers the graph read from it
0cells of the map it votes in
448citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

448 citing papers in PubMed.

  1. Complement component 3c and tumor necrosis factor-α systemic assessment after Candida antigen immunotherapy in cutaneous warts.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. OralNutrients · 2026
    Article
  7. Article
  8. The unique Efg1 fungal virulence regulon in the catheterized bladder environment.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  14. Interactions betweenInfection and immunity · 2026
    Article
  15. Review
  16. Article
  17. International journal of molecular sciences · 2026
    Article
  18. Review
  19. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  20. Review

388 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neil A R GowAberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Frank L van de Veerdonk
Alistair J P Brown
Mihai G Netea

Funding

Biotechnology and Biological Sciences Research Council BB/F00513X/1European Research Council 249793Wellcome TrustWellcome Trust 080088
6 · The paper itself

Abstract

Candida albicans is a common fungal pathogen of humans that colonizes the skin and mucosal surfaces of most healthy individuals. Until recently, little was known about the mechanisms by which mucosal antifungal defences tolerate colonizing C. albicans but react strongly when hyphae of the same microorganism attempt to invade tissue. In this Review, we describe the properties of yeast cells and hyphae that are relevant to their interaction with the host, and the immunological mechanisms that differentially recognize colonizing versus invading C. albicans.

Indexed as

AnimalsCandida albicansCandidiasisCell WallCyclic AMP-Dependent Protein KinasesHumansHyphaeLectins, C-TypeMorphogenesisNod Signaling Adaptor ProteinsSignal TransductionSkinToll-Like ReceptorsCyclic AMP-Dependent Protein KinasesLectins, C-TypeNod Signaling Adaptor ProteinsToll-Like Receptors

Identifiers

PMID22158429
PMCPMC3624162

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.