Evidence map›Paper›PMID 22157123›Full record

ArticleJournal of neurophysiology2012

Segmental differences in firing properties and potassium currents in Drosophila larval motoneurons.

Subhashini Srinivasan, Kimberley Lance, Richard B Levine

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of neurophysiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Multiple Scales of Coordination along the Body Axis duringThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. Control of Sleep Onset by Shal/KThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  3. Article
  4. Article
  5. Article
  6. Preparation of Drosophila central neurons for in situ patch clamping.Journal of visualized experiments : JoVE · 2012
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Subhashini SrinivasanDepartment of Neuroscience, University ofArizona, Tucson, AZ, USA.
Kimberley Lance
Richard B Levine
University of Arizona · US

Funding

NEURAL DEVELOPMENT--INTERCELLULAR AND HUMORAL CONTROLP01NS028495 · NINDS · UNIVERSITY OF ARIZONA · PI LEVINE, RICHARD B · 1990 to 2005
$5.9M
NINDS NIH HHS NS28495
6 · The paper itself

Abstract

Potassium currents play key roles in regulating motoneuron activity, including functional specializations that are important for locomotion. The thoracic and abdominal segments in the Drosophila larval ganglion have repeated arrays of motoneurons that innervate body-wall muscles used for peristaltic movements during crawling. Although abdominal motoneurons and their muscle targets have been studied in detail, owing, in part, to their involvement in locomotion, little is known about the cellular properties of motoneurons in thoracic segments. The goal of this study was to compare firing properties among thoracic motoneurons and the potassium currents that influence them. Whole-cell, patch-clamp recordings performed from motoneurons in two thoracic and one abdominal segment revealed both transient and sustained voltage-activated K(+) currents, each with Ca(++)-sensitive and Ca(++)-insensitive [A-type, voltage-dependent transient K(+) current (I(Av))] components. Segmental differences in the expression of voltage-activated K(+) currents were observed. In addition, we demonstrate that Shal contributes to I(Av) currents in the motoneurons of the first thoracic segment.

Indexed as

AbdomenAction PotentialsAnimalsDrosophilaInterneuronsLarvaMotor NeuronsPotassium ChannelsThoraxPotassium Channels

Identifiers

PMID22157123
PMCPMC3311690
OpenAlexW2060116518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.