ArticleJournal of neurophysiology2012
Decoding 3D reach and grasp from hybrid signals in motor and premotor cortices: spikes, multiunit activity, and local field potentials.
Article in Journal of neurophysiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
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Who cites it
94 citing papers in PubMed.
- Stable long-term BCI-enabled communication in ALS and locked-in syndrome using LFP signals.Journal of neurophysiology · 2018Trial
- Non-causal spike filtering improves decoding of movement intention for intracortical BCIs.Journal of neuroscience methods · 2014Trial
- Parietal oscillations code nonvisual reach targets relative to gaze and body.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation.Nature biomedical engineering · 2026Article
- Cortical representation of multidimensional handwriting movement and implications for neuroprostheses.Nature communications · 2026Article
- Regional specialization of movement encoding across the primate sensorimotor cortex.Nature communications · 2025Article
- Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces.APL bioengineering · 2025Article
- Multi-gesture drag-and-drop decoding in a 2D iBCI control task.Journal of neural engineering · 2025Article
- Dynamical modeling of nonlinear latent factors in multiscale neural activity with real-time inference.Advances in neural information processing systems · 2025Article
- Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks.Nature neuroscience · 2024Article
- Article
- Differential Modulation of Local Field Potentials in the Primary and Premotor Cortices during Ipsilateral and Contralateral Reach to Grasp in Macaque Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Event detection and classification from multimodal time series with application to neural data.Journal of neural engineering · 2024Article
- Multimodal subspace identification for modeling discrete-continuous spiking and field potential population activity.Journal of neural engineering · 2024Article
- Dynamical flexible inference of nonlinear latent factors and structures in neural population activity.Nature biomedical engineering · 2024Article
- Decoding hand kinetics and kinematics using somatosensory cortex activity in active and passive movement.iScience · 2023Article
- Ventral premotor cortex encodes task relevant features during eye and head movements.Scientific reports · 2022Article
- Large-scale all-optical dissection of motor cortex connectivity shows a segregated organization of mouse forelimb representations.Cell reports · 2022Article
- Decoding of attentional state using local field potentials.Current opinion in neurobiology · 2022Review
- Article
34 more citing papers are in PubMed but not listed here.
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4 authors.
Funding
Abstract
Neural activity in motor cortex during reach and grasp movements shows modulations in a broad range of signals from single-neuron spiking activity (SA) to various frequency bands in broadband local field potentials (LFPs). In particular, spatiotemporal patterns in multiband LFPs are thought to reflect dendritic integration of local and interareal synaptic inputs, attentional and preparatory processes, and multiunit activity (MUA) related to movement representation in the local motor area. Nevertheless, the relationship between multiband LFPs and SA, and their relationship to movement parameters and their relative value as brain-computer interface (BCI) control signals, remain poorly understood. Also, although this broad range of signals may provide complementary information channels in primary (MI) and ventral premotor (PMv) areas, areal differences in information have not been systematically examined. Here, for the first time, the amount of information in SA and multiband LFPs was compared for MI and PMv by recording from dual 96-multielectrode arrays while monkeys made naturalistic reach and grasp actions. Information was assessed as decoding accuracy for 3D arm end point and grip aperture kinematics based on SA or LFPs in MI and PMv, or combinations of signal types across areas. In contrast with previous studies with ≤16 simultaneous electrodes, here ensembles of >16 units (on average) carried more information than multiband, multichannel LFPs. Furthermore, reach and grasp information added by various LFP frequency bands was not independent from that in SA ensembles but rather typically less than and primarily contained within the latter. Notably, MI and PMv did not show a particular bias toward reach or grasp for this task or for a broad range of signal types. For BCIs, our results indicate that neuronal ensemble spiking is the preferred signal for decoding, while LFPs and combined signals from PMv and MI can add robustness to BCI control.
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