Evidence map›Paper›PMID 22156698›Full record

ArticleStroke2012

Can genes modify stroke outcome and by what mechanisms?

Roger P Simon, Robert Meller, An Zhou, David Henshall

Abstract read
In one paragraph

Article in Stroke, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Correction to: Neuroimmune Response in Ischemic Preconditioning.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2018
    Article
  3. Early Rehabilitation After Stroke: a Narrative Review.Current atherosclerosis reports · 2017
    Review
  4. Plasticity of Sensorimotor Networks: Multiple Overlapping Mechanisms.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2017
    Review
  5. Neuroimmune Response in Ischemic Preconditioning.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2016
    Review
  6. Genetics as a molecular window into recovery, its treatment, and stress responses after stroke.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2016
    Review
  7. Review
  8. Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2013
    Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Roger P SimonThe Neuroscience Institute, Morehouse Medical School, 720 Westview Dr, SW, Atlanta, GA, 30310-1495, USA. rsimon@msm.edu
Robert Meller
An Zhou
David Henshall

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
TRANSCRIPTION FACTORS AND PROSTATE CANCERG12RR003034 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI ZHAO, XUEYING · 1986 to 2011
$32.4M
Research Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI JOHNSON, PRISCILLA SUE · 2012 to 2018
$24.8M
WARCEFU54RR026137 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI FOREMAN, MARILYN G. · 2009 to 2011
$14.6M
New Gene Expression in Cell Culture Models of IschemiaP01NS035965 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SIMON, ROGER PANCOAST · 1997 to 2007
$9.4M
MOLECULAR MECHANISMS OF SEIZURE INDUCED BRAIN INJURYR01NS039016 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SIMON, ROGER PANCOAST · 1999 to 2009
$2.6M
Rapid ischemic tolerance: Synaptic re-organization and reduced excitotoxicityR01NS059588 · NINDS · MOREHOUSE SCHOOL OF MEDICINE · PI MELLER, ROBERT · 2008 to 2012
$1.6M
Brain ischemia attenuates neuropeptide biosynthesisR01NS046560 · NINDS · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI ZHOU, AN · 2005 to 2008
$1.2M
NCRR NIH HHS G12 RR003034NCRR NIH HHS G12-RR03034NCRR NIH HHS U54 RR026137NIMHD NIH HHS S21 MD000101NIMHD NIH HHS U54 MD007588NINDS NIH HHS P01 NS035965NINDS NIH HHS R01 NS039016NINDS NIH HHS R01NS039016NINDS NIH HHS R01 NS046560NINDS NIH HHS R01NS046560NINDS NIH HHS R01 NS059588NINDS NIH HHS R01NS059588
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GenomicsHumansStroke

Identifiers

PMID22156698
PMCPMC3282466

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.