Evidence map›Paper›PMID 22156217›Full record

ReviewTopics in antiviral medicine2011

Safer conception interventions for HIV-affected couples: implications for resource-constrained settings.

Rachelle J Chadwick, Joanne E Mantell, Jennifer Moodley, Jane Harries, Virginia Zweigenthal, Diane Cooper

Abstract readReview
In one paragraph

Review in Topics in antiviral medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Article
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  5. Predictors of Safer Conception Practices Among HIV-Infected Women in Northern Nigeria.International journal of health policy and management · 2019
    Article
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  10. Review
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  13. A Novel Safer Conception Counseling Toolkit for the Prevention of HIV: A Mixed-Methods Evaluation in Kisumu, Kenya.AIDS education and prevention : official publication of the International Society for AIDS Education · 2016
    Article
  14. Article
  15. Article
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rachelle J ChadwickWomen's Health Research Unit, School of Public Health and Family Medicine, University of Cape Town, South Africa.
Joanne E Mantell
Jennifer Moodley
Jane Harries
Virginia Zweigenthal
Diane Cooper
University of Cape Town · ZA

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
A Structural Intervention To Integrate Reproductive Health Into HIV CareR01MH078770 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANTELL, JOANNE ELLEN · 2007 to 2011
$2.5M
NIMH NIH HHS P30 MH043520NIMH NIH HHS P30-MH43520NIMH NIH HHS R01-MH078770
6 · The paper itself

Abstract

Developing and testing safer conception methods that reduce HIV transmission to HIV-seronegative partners in serodiscordant couples and reduce superinfection in HIV-seroconcordant couples is a crucial but often unaddressed component of HIV prevention programs. Most research has focused on developed-world settings, where "high-technology" assisted reproduction techniques are used for HIV-serodiscordant couples in which the male is HIV-infected. There is a dearth of research on safer conception methods for HIV-seropositive women and "low-technology" harm-reduction strategies for HIV-affected couples, including vaginal insemination for HIV-seropositive women and natural conception methods for HIV-seroconcordant and -serodiscordant couples. This review summarizes international studies of safer conception interventions for HIV-affected couples, with a focus on feasibility in public-sector health settings where assisted reproductive technology is not readily available. Given that such low-technology options are feasible in most settings, well-designed, prospective interventions offering low-technology safer conception methods need to be developed and tested.

Indexed as

FertilizationDisease Transmission, InfectiousFamily CharacteristicsHarm ReductionHIV InfectionsHumansSexual Partners

Identifiers

PMID22156217
PMCPMC6148878
OpenAlexW118549567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.