Evidence map›Paper›PMID 22154987›Full record

SynthesisClinical nutrition (Edinburgh, Scotland)2012

Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials.

George A Kelley, Kristi S Kelley, Susan Roberts, William Haskell

Abstract readComparative StudyMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical nutrition (Edinburgh, Scotland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 12 pooled it
26.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 12 syntheses or guidelines pooled it, 122 citations in OpenAlex.

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  9. Effect of childhood obesity prevention programmes on blood lipids: a systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2014
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  14. International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

George A KelleyDepartment of Community Medicine, West Virginia University, Morgantown, WV 26506-9190, United States. gkelley@hsc.wvu.edu
Kristi S Kelley
Susan Roberts
William Haskell
Stanford University · USTufts University · USWest Virginia University · USWest Virginia University Hospitals · US

Funding

Aerobic Exercise, Diet and Cholesterol: A Meta-AnalysisR01HL069802 · NHLBI · WEST VIRGINIA UNIVERSITY · PI KELLEY, GEORGE A · 2002 to 2010
$866k
NHLBI NIH HHS R01 HL069802
6 · The paper itself

Abstract

objectiveGiven that previous studies have reached conflicting conclusions regarding the effects of diet (D), aerobic exercise (E) or both (DE) on blood lipid and lipoprotein concentrations in adults, the meta-analytic approach was used to address this issue. DATA SOURCES: Nine electronic databases, cross-referencing, and expert review. STUDY SELECTION: Randomized controlled trials ≥ 4 weeks that included a D, E, DE and control (C) group in adults ≥ 18 years of age and in which data for one or more of the following were available: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG). DATA EXTRACTION: Dual data extraction by the first two authors. STATISTICAL ANALYSIS: Random-effects models as well as mixed-effects models for between-group differences.

resultsSeven-hundred and eighty-eight men and women from 6 studies were included. Non-overlapping 95% confidence intervals were observed for D and DE with respect to lowering TC, LDL-C and TG while reductions in E were limited to TG. No significant changes in HDL-C were observed. When compared to E, reductions in TC and LDL-C were greater for D and DE (p < 0.05 for all).

conclusionsDiet, especially DE, are superior to E for improving selected lipids and lipoproteins in adults.

Indexed as

DietAdultCholesterol, HDLCholesterol, LDLDatabases, FactualExerciseFemaleHumansMaleRandomized Controlled Trials as TopicTreatment OutcomeTriglyceridesCholesterol, HDLCholesterol, LDLTriglycerides

Identifiers

PMID22154987
PMCPMC3311746
OpenAlexW1964173592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.