Trial reportUrologic oncology2013
The Personal Patient Profile-Prostate decision support for men with localized prostate cancer: a multi-center randomized trial.
Trial report in Urologic oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 10 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- A mixed methods systematic review of cancer treatment decision-making in vulnerable populations.Patient education and counseling · 2026Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- Decision coaching for people making healthcare decisions.The Cochrane database of systematic reviews · 2021Pooled it
- Interventions that Facilitate Shared Decision-Making in Cancers with Active Surveillance as Treatment Option: a Systematic Review of Literature.Current oncology reports · 2020Pooled it
- A systematic review of the feasibility, acceptability, and efficacy of online supportive care interventions targeting men with a history of prostate cancer.Journal of cancer survivorship : research and practice · 2019Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017Pooled it
- Are cancer-related decision aids appropriate for socially disadvantaged patients? A systematic review of US randomized controlled trials.BMC medical informatics and decision making · 2016Pooled it
- Patient-mediated knowledge translation (PKT) interventions for clinical encounters: a systematic review.Implementation science : IS · 2016Pooled it
- Features of Computer-Based Decision Aids: Systematic Review, Thematic Synthesis, and Meta-Analyses.Journal of medical Internet research · 2016Pooled it
- [Treatment of nonmetastatic prostate cancer: a systematic review of interactive, personalized patient decision aids].Der Urologe. Ausg. A · 2014Pooled it
- Individual Characteristics in the Comprehension of Pandemic Video Communication: Randomized Controlled Between-Subjects Design.Journal of medical Internet research · 2024Trial
- Concordance between influential adverse treatment outcomes and localized prostate cancer treatment decisions.BMC medical informatics and decision making · 2022Trial
- Development and Pilot Evaluation of a Decision Aid for Small Kidney Masses.Journal of the American College of Radiology : JACR · 2022Trial
- Effectiveness of Decision Aid in Men with Localized Prostate Cancer: a Multicenter Randomized Controlled Trial at Tertiary Referral Hospitals in an Asia Pacific Country.Journal of cancer education : the official journal of the American Association for Cancer Education · 2022Trial
- Differences in treatment choices between prostate cancer patients using a decision aid and patients receiving care as usual: results from a randomized controlled trial.World journal of urology · 2021Trial
- Head to head randomized trial of two decision aids for prostate cancer.BMC medical informatics and decision making · 2021Trial
- Assigning value to preparation for prostate cancer decision making: a willingness to pay analysis.BMC medical informatics and decision making · 2019Trial
- Decision Support with the Personal Patient Profile-Prostate: A Multicenter Randomized Trial.The Journal of urology · 2018Trial
- Patient and family communication during consultation visits: The effects of a decision aid for treatment decision-making for localized prostate cancer.Patient education and counseling · 2017Trial
- Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 10 institutions in 2 countries.
Funding
Abstract
objectiveThe purpose of this trial was to compare usual patient education plus the Internet-based Personal Patient Profile-Prostate, vs. usual education alone, on conflict associated with decision making, plus explore time-to-treatment, and treatment choice.
methodsA randomized, multi-center clinical trial was conducted with measures at baseline, 1-, and 6 months. Men with newly diagnosed localized prostate cancer (CaP) who sought consultation at urology, radiation oncology, or multi-disciplinary clinics in 4 geographically-distinct American cities were recruited. Intervention group participants used the Personal Patient Profile-Prostate, a decision support system comprised of customized text and video coaching regarding potential outcomes, influential factors, and communication with care providers. The primary outcome, patient-reported decisional conflict, was evaluated over time using generalized estimating equations to fit generalized linear models. Additional outcomes, time-to-treatment, treatment choice, and program acceptability/usefulness, were explored.
resultsA total of 494 eligible men were randomized (266 intervention; 228 control). The intervention reduced adjusted decisional conflict over time compared with the control group, for the uncertainty score (estimate -3.61; (confidence interval, -7.01, 0.22), and values clarity (estimate -3.57; confidence interval (-5.85,-1.30). Borderline effect was seen for the total decisional conflict score (estimate -1.75; confidence interval (-3.61,0.11). Time-to-treatment was comparable between groups, while undecided men in the intervention group chose brachytherapy more often than in the control group. Acceptability and usefulness were highly rated.
conclusionThe Personal Patient Profile-Prostate is the first intervention to significantly reduce decisional conflict in a multi-center trial of American men with newly diagnosed localized CaP. Our findings support efficacy of P3P for addressing decision uncertainty and facilitating patient selection of a CaP treatment that is consistent with the patient values and preferences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.