Evidence map›Paper›PMID 22153351›Full record

ReviewCurrent opinion in structural biology2012

Bacterial plasmid partition machinery: a minimalist approach to survival.

Maria A Schumacher

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Plasmid-free cheater cells commonly evolve during laboratory growth.Applied and environmental microbiology · 2024
    Article
  3. Review
  4. Plasmid co-infection: linking biological mechanisms to ecological and evolutionary dynamics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Maria A SchumacherDepartment of Biochemistry, Duke University School of Medicine, Durham, NC 27710, USA. maria.schumacher@duke.edu

Funding

Structural studies on the P1 plasmid partition apparatus.R01GM074815 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SCHUMACHER, MARIA · 2006 to 2009
$720k
NIGMS NIH HHS R01 GM074815
6 · The paper itself

Abstract

The accurate segregation or partition of replicated DNA is essential for ensuring stable genome transmission. Partition of bacterial plasmids requires only three elements: a centromere-like DNA site and two proteins, a partition NTPase, and a centromere-binding protein (CBP). Because of this simplicity, partition systems have served as tractable model systems to study the fundamental molecular mechanisms required for DNA segregation at an atomic level. In the last few years, great progress has been made in this endeavor. Surprisingly, these studies have revealed that although the basic partition components are functionally conserved between three types of plasmid partition systems, these systems employ distinct mechanisms of DNA segregation. This review summarizes the molecular insights into plasmid segregation that have been achieved through these recent structural studies.

Indexed as

BacteriaCentromereDNA, BacterialDNA-Binding ProteinsMicrobial ViabilityPlasmidsDNA, BacterialDNA-Binding Proteins

Identifiers

PMID22153351
PMCPMC4824291

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.