ReviewCurrent opinion in cell biology2012
Regulation of BMP activity and range in Drosophila wing development.
Review in Current opinion in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Signaling pathways in Drosophila testis niche: Local signals that regulate stem cell fate.Insect science · 2026Review
- Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model.Developmental dynamics : an official publication of the American Association of Anatomists · 2026Article
- Review
- Regulated delivery controlseLife · 2021Article
- Diverse roles of phosphatidate phosphatases in insect development and metabolism.Insect biochemistry and molecular biology · 2021Review
- A unified mechanism for the control of Drosophila wing growth by the morphogens Decapentaplegic and Wingless.PLoS biology · 2021Article
- Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development.PLoS genetics · 2020Article
- Interplay between morphogen-directed positional information systems and physiological signaling.Developmental dynamics : an official publication of the American Association of Anatomists · 2020Review
- Drosophila ML-DmD17-c3 cells respond robustly to Dpp and exhibit complex transcriptional feedback on BMP signaling components.BMC developmental biology · 2019Article
- Inwardly rectifying potassium channels influenceDevelopment (Cambridge, England) · 2017Article
- Precision Optogenetic Tool for Selective Single- and Multiple-Cell Ablation in a Live Animal Model System.Cell chemical biology · 2017Article
- TGF-β signaling in insects regulates metamorphosis via juvenile hormone biosynthesis.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Article
- Proteoglycans and neuronal migration in the cerebral cortex during development and disease.Frontiers in neuroscience · 2015Review
- Paracrine signaling mediated at cell-cell contacts.BioEssays : news and reviews in molecular, cellular and developmental biology · 2015Review
- Smad1 stabilization and delocalization in response to the blockade of BMP activity.Cellular & molecular biology letters · 2013Article
- Fine-tuned shuttles for bone morphogenetic proteins.Current opinion in genetics & development · 2013Review
- The ventral to dorsal BMP activity gradient in the early zebrafish embryo is determined by graded expression of BMP ligands.Developmental biology · 2013Article
- BMP signaling in wing development: A critical perspective on quantitative image analysis.FEBS letters · 2012Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Bone morphogenetic protein (BMP) signaling controls development and maintenance of many tissues. Genetic and quantitative approaches in Drosophila reveal that ligand isoforms show distinct function in wing development. Spatiotemporal control of BMP patterning depends on a network of extracellular proteins Pent, Ltl and Dally that regulate BMP signaling strength and morphogen range. BMP-mediated feedback regulation of Pent, Ltl, and Dally expression provides a system where cells actively respond to, and modify, the extracellular morphogen landscape to form a gradient that exhibits remarkable properties, including proportional scaling of BMP patterning with tissue size and the modulation of uniform tissue growth. This system provides valuable insights into mechanisms that mitigate the influence of variability to regulate cell-cell interactions and maintain organ function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.