Evidence map›Paper›PMID 22152186›Full record

ArticleValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research2011

Preferences for CT colonography and colonoscopy as diagnostic tests for colorectal cancer: a discrete choice experiment.

Kirsten Howard, Glenn Salkeld, Michael Pignone, Peter Hewett, Peter Cheung, Julie Olsen, Wayne Clapton, Ian C Roberts-Thomson

Open access · bronzeAbstract read
In one paragraph

Article in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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  18. CONSUMER PREFERENCES FOR SCANNING MODALITY TO DIAGNOSE FOCAL LIVER LESIONS.International journal of technology assessment in health care · 2015
    Article
  19. Incorporating patients' preferences into medical decision making.Medical care research and review : MCRR · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Kirsten HowardSydney School of Public Health, University of Sydney, Sydney, Australia. kirsten.howard@sydney.edu.au
Glenn Salkeld
Michael Pignone
Peter Hewett
Peter Cheung
Julie Olsen
Wayne Clapton
Ian C Roberts-Thomson
University of Sydney · AUQueen Elizabeth Hospital · AURoyal Adelaide Hospital · AUSA Health · AUUniversity of Adelaide · AU

Funding

Improving Cancer-Related Patient Decision MakingK05CA129166 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PIGNONE, MICHAEL P · 2008 to 2012
$765k
NCI NIH HHS K05 CA129166
6 · The paper itself

Abstract

objectiveComputed tomography colonography (CTC) is an alternative diagnostic test to colonoscopy for colorectal cancer and polyps. The aim of this study was to determine test characteristics important to patients and to examine trade-offs in attributes that patients are willing to accept in the context of the diagnosis of colorectal cancer.

methodsA discrete choice study was used to assess preferences of patients with clinical indications suspicious of colorectal cancer who experienced both CTC and colonoscopy as part of a diagnostic accuracy study in South Australia. Results were analyzed by using a mixed logit model and presented as odds ratios (ORs) for preferring CTC over colonoscopy.

resultsColonoscopy was preferred over CTC as the need for a second procedure after CTC increased (OR of preferring CTC to colonoscopy = 0.013), as the likelihood of missing cancers or polyps increased (OR of preferring CTC to colonoscopy = 0.62), and as CTC test cost increased (OR of preferring CTC to colonoscopy = 0.65-0.80). CTC would be preferred to colonoscopy if a minimal bowel preparation was available (OR = 1.7). Some patients were prepared to trade off the diagnostic and therapeutic advantage of colonoscopy for a CTC study with a less intensive bowel preparation. Preferences also varied significantly with sociodemographic characteristics.

conclusionsDespite CTC's often being perceived as a preferred test, this may not always be the case. Informed decision making for diagnostic tests for colorectal cancer should include discussion of the benefits, downsides, and uncertainties associated with alternative tests, as patients are willing and able to make trade-offs between what they perceive as the advantages and disadvantages of these diagnostic tests.

Indexed as

Choice BehaviorPatient PreferenceAdultAgedAged, 80 and overColonic PolypsColonography, Computed TomographicColonoscopyColorectal NeoplasmsDecision MakingFemaleHumansLogistic ModelsMaleMiddle AgedPilot Projects

Identifiers

PMID22152186
PMCPMC3466595
OpenAlexW2166342942

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.