ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2012
The role of 18FDG PET/CT in the management of colorectal liver metastases.
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy and impact on management of (18)F-FDG PET and PET/CT in colorectal liver metastasis: a meta-analysis and systematic review.European journal of nuclear medicine and molecular imaging · 2015Pooled it
- Limited benefit of additional contrast-enhanced CT to end-of-treatment PET/CT evaluation in patients with follicular lymphoma.Scientific reports · 2021Article
- Article
- Colorectal liver metastases: Current management and future perspectives.World journal of clinical oncology · 2020Review
- Predictors of early recurrence after resection of colorectal liver metastases.World journal of surgical oncology · 2015Article
- Colorectal cancer with liver metastases: neoadjuvant chemotherapy, surgical resection first or palliation alone?World journal of gastroenterology · 2014Review
- Nuclear imaging for functional evaluation and theragnosis in liver malignancy and transplantation.World journal of gastroenterology · 2014Article
- The influence of FDG PET-CT on the detection of extrahepatic disease in patients being considered for resection of colorectal liver metastasis.Annals of the Royal College of Surgeons of England · 2014Article
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6 authors.
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Abstract
introductionSurgical resection remains the only potentially curative treatment for colorectal liver metastases (CLM). However, involvement of both the hepatic lobes or extrahepatic disease (EHD) can be a contra-indication for resection. The aim of the present study was to examine the addition of combined positron emission and computed tomography (PET/CT) to CLM staging to assess the effects upon staging and management.
methodsAll CLM patients referred to a single centre between January 2005 and January 2009 were prospectively included. All underwent routine staging (clinical examination and computed tomography), followed by a whole body (18) fluoro-deoxy-glucose ((18)FDG)-PET/CT scan and Fong clinical risk score calculation.
resultsSixty-four patients were included [63% male with a median age of 63 years (age range 32-79 years)]. The addition of PET/CT led to disease upstaging in 20 patients (31%) and downstaging in two patients (3%). EHD was found in 24% of low-risk patients (Fong score 0-2) as compared with 44% of high-risk patients (Fong score 3-5) (P= 0.133). There was a trend towards a greater influence upon management in patients with a low score (44% vs. 17%; P= 0.080).
conclusionThe addition of PET/CT led to management changes in over one-third of patients but there was no correlation between alterations in staging or management and the Fong clinical risk score; suggesting that PET/CT should be utilized, where available, in the pre-operative staging of CLM patients.
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