Evidence map›Paper›PMID 22149767›Full record

ArticleAIDS patient care and STDs2012

The impact of stigma on medication adherence among HIV-positive adolescent and young adult females and the moderating effects of coping and satisfaction with health care.

Jaime Martinez, Gary Harper, Russell A Carleton, Sybil Hosek, Kelly Bojan, Gretchen Clum, Gretchen Glum, Jonathan Ellen, Adolescent Medicine Trials Network

Erratum issuedOpen access · greenAbstract readMulticenter Study
In one paragraph

Article in AIDS patient care and STDs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 70 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 6 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 6 syntheses or guidelines pooled it, 148 citations in OpenAlex.

  1. Psychometric Properties of the Berger HIV Stigma Scale: A Systematic Review.International journal of environmental research and public health · 2021
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
    Glum, Gretchen [corrected to Clum, Gretchen]
5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jaime MartinezDivision of Adolescent and Young Adult Medicine, Stroger Hospital of Cook County, Chicago, Illinois 60612, USA. jmart312@aol.com
Gary Harper
Russell A Carleton
Sybil Hosek
Kelly Bojan
Gretchen Clum
Gretchen Glum
Jonathan Ellen
Adolescent Medicine Trials Network
DePaul University · USJohn H. Stroger, Jr. Hospital of Cook County · USJohns Hopkins University · USRuth M. Rothstein CORE Center · USTulane University · US

Funding

Adol. Medicine Trials Network for HIV/AIDS InterventionsU01HD040474 · NICHD · WESTAT, INC. · PI HARRIS, DONALD ROBERT · 2001 to 2016
$114.4M
LEADERSHIP GROUP FOR ADOLESCENT MEDICINE TRIALS NETWORKU01HD040533 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILSON, CRAIG M · 2001 to 2016
$76.4M
Stroger/CORE Chicago Adolescent Trials Unit (ATU)U01HD040515 · NICHD · HEKTOEN INSTITUTE FOR MEDICAL RESEARCH · PI HENRY-REID, LISA MICHELLE · 2001 to 2015
$9.4M
NEW ORLEANS ADOLESCENT MEDICINE TRIALS UNITU01HD040470 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI ABDALIAN, SUE ELLEN · 2001 to 2015
$8.8M
Drug Use and HIV Infected Female Adolescents'Care UseR01DA014706 · NIDA · JOHNS HOPKINS UNIVERSITY · PI ELLEN, JONATHAN M · 2001 to 2004
$4.8M
NICHD NIH HHS U01 HD040470NICHD NIH HHS U01 HD040474NICHD NIH HHS U01 HD040515NICHD NIH HHS U01 HD040533NICHD NIH HHS U01 HD40533NIDA NIH HHS R01DA14706
6 · The paper itself

Abstract

To explore whether HIV stigma negatively impacts adherence to antiviral medications in HIV-infected adolescent women, moderational analysis was conducted and factors identified that could alter said relationship. Study participants were 178 adolescent females age 15-24, enrolled between 2003-2005, from 5 different cities and 60 provided adherence information. Findings reported by this cohort of 60 adolescent women included: medication adherence, 64.3% reporting adherence at baseline and 45.0% at 12 months; HIV stigma score of 57.60 (standard deviation [SD], 11.83; range, 25-86). HIV stigma was not found to be a significant predictor when binary logit regression was run with medication adherence at 1 year. Using moderational analysis, factors that could moderate stigma's effect on medication adherence was still pursued and identified the following to be significant at 12 months: health care satisfaction (B = -0.020, standard error [SE] = 0.010, p < .05); and Coping (proactive coping strategies [B = 0.012, SE = 0.005, p < .05]; turning to family [B = 0.012, SE = 0.016, p < 0.05]; spiritual coping [B = 0.021, SE = 0.010, p < 0.05]; professional help [B = 0.021, SE = 0.010, p < 0.05]; physical diversions [B = 0.016, SE = 0.007, p < 0.05]). Factors that had no significant moderating effects included: social support measures (mean = 74.9; median = 74.0) and depression score greater than 16 = 43%. We conclude that HIV-infected adolescent women experience HIV stigma and poor adherence over time. Factors like health care satisfaction and coping may minimize stigma's effect on medication adherence. Our findings are tempered by a small sample size and lack of a direct relationship between stigma and adherence on binary logit regression analysis.

Indexed as

Adaptation, PsychologicalPatient SatisfactionSocial StigmaAdolescentAnti-HIV AgentsCohort StudiesDepressionDrug MonitoringFemaleHealth Services AccessibilityHIV SeropositivityHumansMedication AdherenceQuality of LifeSelf EfficacySocial SupportAnti-HIV Agents

Identifiers

PMID22149767
PMCPMC3266519
OpenAlexW2034492708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.