ArticleThe Angle orthodontist2012
Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning.
Article in The Angle orthodontist, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Can exposure to panoramic radiographs induce genotoxic effects on the oral epithelium? A systematic review with meta-analysis.Dento maxillo facial radiology · 2022Pooled it
- Genotoxic and cytotoxic effects of cone beam computed tomography on exfoliated epithelial cells in different age groups.BMC oral health · 2025Article
- Genotoxicity and cytotoxicity effects of x-rays on the oral mucosa epithelium at different fields of view: A cone beam computed tomography technique.Caspian journal of internal medicine · 2023Article
- Biomonitoring of Genotoxic Effect in Children Exposed to Dental Radiographs during Pulpectomy Procedure-BMCyt Assay.International journal of clinical pediatric dentistry · 2022Article
- Radiobiological risks following dentomaxillofacial imaging: should we be concerned?Dento maxillo facial radiology · 2021Review
- Low-dose radiations derived from cone-beam CT induce transient DNA damage and persistent inflammatory reactions in stem cells from deciduous teeth.Dento maxillo facial radiology · 2019Article
- Evidence of genotoxicity and cytotoxicity of X-rays in the oral mucosa epithelium of adults subjected to cone beam CT.Dento maxillo facial radiology · 2018Article
- Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures.Environmental health : a global access science source · 2017Article
- Genotoxic effects of X-rays in buccal mucosal cells in children subjected to dental radiographs.BDJ open · 2016Article
- Mutagenicity and cytotoxicity in patients submitted to ionizing radiation.The Angle orthodontist · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated buccal mucosa cells from children undergoing orthodontic radiographs. MATERIALS AND
methodsA total of 25 healthy children undergoing orthodontic therapy partook in a complete set of orthodontic radiographs (lateral cephalographic, posteroanterior cephalographic, panoramic, full periapical exam, and bitewing). The micronucleus test in the buccal exfoliated cells was applied. The paired-samples t-test and the Wilcoxon test were used to compare the frequencies of alterations before and after X-ray exposure.
resultsWe found no statistically significant differences (P > .05) between micronucleated buccal mucosa cells before and after exposure to radiation. However, radiation did cause other nuclear alterations closely related to cytotoxicity (P = .007).
conclusionAccording to the micronucleus test, the complete set of radiographs requested in the orthodontic planning may not be a factor that induces chromosomal damage, but it is able to promote cytotoxicity.
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