Evidence map›Paper›PMID 22148740›Full record

ReviewACS chemical biology2012

Novel modifications in RNA.

Kelly Phelps, Alexi Morris, Peter A Beal

Open access · greenAbstract readReview
In one paragraph

Review in ACS chemical biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 68 citations in OpenAlex.

  1. Synthesis of Oligoribonucleotides Containing a 2'-Amino-5'-The Journal of organic chemistry · 2021
    Article
  2. Article
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  5. Article
  6. Article
  7. Article
  8. Review
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  11. Article
  12. Review
  13. Article
  14. The delivery of therapeutic oligonucleotides.Nucleic acids research · 2016
    Review
  15. Article
  16. Article
  17. Expanding the Scope of 2'-SCF3 Modified RNA.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kelly PhelpsDepartment of Chemistry, University of California, Davis, 95616, United States.
Alexi Morris
Peter A Beal
University of California, Davis · US

Funding

The Bioorganic Chemistry Of RNA Editing By ADARSR01GM061115 · NIGMS · UNIVERSITY OF UTAH · PI BEAL, PETER A. · 2001 to 2020
$4.5M
Nucleobase analogs for next generation siRNAsR01GM080784 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BEAL, PETER A. · 2007 to 2020
$3.5M
NIGMS NIH HHS R01 GM061115NIGMS NIH HHS R01GM061115NIGMS NIH HHS R01 GM080784NIGMS NIH HHS R01GM080784
6 · The paper itself

Abstract

The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs. In this review, we describe recent discoveries in these areas with a focus on RNA modifications that introduce spectroscopic tags, reactive handles, or new recognition properties.

Indexed as

AlkynesAzidesBinding SitesClick ChemistryDrug DesignFluorescent DyesFree RadicalsHumansInverted Repeat SequencesMagnetic Resonance SpectroscopyMolecular ProbesMolecular Sequence DataNucleosidesNucleotide MotifsRNA, Small InterferingSpectrometry, FluorescenceAlkynesAzidesdifluorotolueneFluorescent DyesFree RadicalsMolecular ProbesNucleosidesRNA, Small InterferingToluene

Identifiers

PMID22148740
PMCPMC3270579
OpenAlexW2120229348

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.