ArticleJournal of Korean medical science2011
Comparison of clinico-physiologic and CT imaging risk factors for COPD exacerbation.
Article in Journal of Korean medical science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- CT densitometry in emphysema: a systematic review of its clinical utility.International journal of chronic obstructive pulmonary disease · 2018Pooled it
- Efficacy and Safety of Roflumilast in Korean Patients with COPD.Yonsei medical journal · 2016Trial
- Automatically Explaining Machine Learning Predictions on Severe Chronic Obstructive Pulmonary Disease Exacerbations: Retrospective Cohort Study.JMIR medical informatics · 2022Article
- Developing a Machine Learning Model to Predict Severe Chronic Obstructive Pulmonary Disease Exacerbations: Retrospective Cohort Study.Journal of medical Internet research · 2022Article
- Phenotyping COPD Patients with Emphysema Distribution Using Quantitative CT Measurement; More Severe Airway Involvement in Lower Dominant Emphysema.International journal of chronic obstructive pulmonary disease · 2022Article
- Deep radiomics-based survival prediction in patients with chronic obstructive pulmonary disease.Scientific reports · 2021Article
- Using Computational Methods to Improve Integrated Disease Management for Asthma and Chronic Obstructive Pulmonary Disease: Protocol for a Secondary Analysis.JMIR research protocols · 2021Article
- A novel CT-emphysema index/FEVInternational journal of chronic obstructive pulmonary disease · 2018Article
- Study Design and Outcomes of Korean Obstructive Lung Disease (KOLD) Cohort Study.Tuberculosis and respiratory diseases · 2014Article
- Comorbidities of chronic obstructive pulmonary disease in Koreans: a population-based study.Journal of Korean medical science · 2012Article
- Relationship between current smoking, visual CT findings and emphysema index in cigarette smokers.Clinical imagingArticle
- Clinical and pulmonary functions profiling of patients with chronic obstructive pulmonary disease experiencing frequent acute exacerbations.Lung India : official organ of Indian Chest SocietyArticle
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Authors and funding
21 authors.
Funding
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Abstract
To date, clinico-physiologic indices have not been compared with quantitative CT imaging indices in determining the risk of chronic obstructive pulmonary disease (COPD) exacerbation. We therefore compared clinico-physiologic and CT imaging indices as risk factors for COPD exacerbation in patients with COPD. We retrospectively analyzed 260 COPD patients from pulmonary clinics at 11 hospitals in Korea from June 2005 to November 2009 and followed-up for at least one year. At the time of enrollment, none of these patients had COPD exacerbations for at least 2 months. All underwent clinico-physiologic and radiological evaluation for risk factors of COPD exacerbation. After 1 yr, 106 of the 260 patients had at least one exacerbation of COPD. Multiple logistic regression analysis showed that old age, high Charlson Index, and low FEV(1) were significant in a clinico-physiologic model, with C-statistics of 0.69, and that increased age and emphysema index were significant in a radiologic model, with C-statistics of 0.64. The difference between the two models was statistically significant (P = 0.04 by bootstrap analysis). Combinations of clinico-physiologic risk factors may be better than those of imaging risk factors in predicting COPD exacerbation.
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