ArticleWorld journal of gastroenterology2011
Morphological effects of autoclaved diet on the myenteric neurons of rats.
Article in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors at 1 institution in 1 country.
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Abstract
aimTo evaluate the effect of autoclaved diet on the jejunum neurons of the myenteric plexus of rats during their growth.
methodsThe experimental groups were made up of rats going through weaning whose mothers received either an autoclaved or a non-autoclaved diet during gestation and lactation, and rats that were fed the same diet as their mothers during the post-weaning period. In order to measure the neurons' body profile and to quantify the number of neurons per area, preparations were stained by the nicotinamide adenine dinucleotide-diaphorase method.
resultsNo significant changes were observed in rats' body weight or in the number of neurons regardless of the diet used (P > 0.05). There was a decrease in the jejunum-ileum length in rats treated with an autoclaved diet (P < 0.05). An increase in the neuronal cross-sectional area was seen in rats that had received the autoclaved diet, an effect that was significant for animals undergoing weaning. In addition, all observed factors showed significant differences when related to the age of the animals.
conclusionThe autoclaved diet did not alter the quantity of neurons, but increased their cell body area, suggesting changes similar to those observed in protein deficiency.
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