ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2012
Reduced stress dose with rapid acquisition CZT SPECT MPI in a non-obese clinical population: comparison to coronary angiography.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Diagnostic performance of myocardial perfusion imaging with conventional and CZT single-photon emission computed tomography in detecting coronary artery disease: A meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Pooled it
- Development and validation of a patient-tailored dose regime in myocardial perfusion imaging using CZT-SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Trial
- Shortened acquisition time or reduced-activity dose for gated myocardial perfusion SPECT with new reconstruction algorithm.The international journal of cardiovascular imaging · 2013Trial
- Recent Progress in Myocardial Perfusion Imaging Techniques.Nuclear medicine and molecular imaging · 2024Review
- Article
- Diagnostic analysis of new quantitative parameters of low-dose dynamic myocardial perfusion imaging with CZT SPECT in the detection of suspected or known coronary artery disease.The international journal of cardiovascular imaging · 2021Article
- Assessment of four different cardiac softwares for evaluation of LVEF with CZT-SPECT vs CMR in 48 patients with recent STEMI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Dedicated cardiac CZT SPECT is steadily moving to achieve its destiny.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Comparison of CZT SPECT and conventional SPECT for assessment of contractile function, mechanical synchrony and myocardial scar in patients with heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- High-speed scanning of planar images showingEJNMMI research · 2019Article
- Striking a balance in the discussion of the benefits of imaging tests and risks of radiation exposure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Impact of data-driven cardiac respiratory motion correction on the extent and severity of myocardial perfusion defects with free-breathing CZT SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- What is the value of motion and thickening in gated myocardial perfusion SPECT?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Effect of a patient-specific minimum activity in stress myocardial perfusion imaging using CZT-SPECT: Prognostic value, radiation dose, and scan outcome.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Myocardial perfusion imaging: Lessons learned and work to be done-update.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Review
- The radiation dose to overweighted patients undergoing myocardial perfusion SPECT can be significantly reduced: validation of a linear weight-adjusted activity administration protocol.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Prognostic value of a faster, low-radiation myocardial perfusion SPECT protocol in a CZT camera.The international journal of cardiovascular imaging · 2017Article
- Feasibility of data-driven cardiac respiratory motion correction of myocardial perfusion CZT SPECT: A pilot study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Myocardial perfusion imaging in women for the evaluation of stable ischemic heart disease-state-of-the-evidence and clinical recommendations.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Evaluation of general-purpose collimators against high-resolution collimators with resolution recovery with a view to reducing radiation dose in myocardial perfusion SPECT: A preliminary phantom study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCadmium Zinc Telluride (CZT) SPECT camera technology has the potential to reduce patient's radiation exposure and shorten imaging time. This study evaluated the correlation of low stress tracer dose, rapid CZT SPECT myocardial perfusion imaging (MPI) to coronary angiography in a <200-lbs population to further validate its ability to achieve both goals while preserving diagnostic accuracy.
methodsAll patients who had a low-dose stress (≤15 mCi) Tc-99m sestamibi SPECT MPI study using a CZT camera (GE Discovery NM 530c) with 3- to 5-minute image acquisition over a 2-year period followed by a coronary angiogram within 2 months were included. Patients with a history of coronary revascularization, left ventricular dysfunction, and LBBB or paced rhythms were excluded. Both MPI studies and coronary angiograms were interpreted by blinded readers and coronary artery disease (CAD) was defined as ≥70% stenosis.
resultsA total of 71 patients were included with a mean age of 64 years, 55% male, and a BMI of 25.4 kg/m(2) with an average stress dose of 13.3 mCi. Exercise stress was performed in 54% of patients and vasodilator pharmacologic stress in 46%. Sensitivity was 89%, specificity was 66%, and accuracy was 78% for detecting obstructive CAD.
conclusionsIn this group of non-obese patients undergoing low stress dose imaging, high-efficiency CZT SPECT imaging demonstrated a high sensitivity, specificity, and accuracy for detecting obstructive epicardial CAD with a greatly reduced imaging time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.