Trial reportJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2012
Quantitative I-123 mIBG SPECT in differentiating abnormal and normal mIBG myocardial uptake.
Trial report in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 55 citations in OpenAlex.
- Application ofAmerican journal of translational research · 2026Article
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- F-18 meta-fluorobenzylguanidine PET imaging of myocardial sympathetic innervation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Methods of calculatingAnnals of nuclear medicine · 2022Article
- Convolutional neural network-based automatic heart segmentation and quantitation inEJNMMI research · 2021Article
- Uniformity of cardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Quality and utility of [Annals of nuclear medicine · 2021Article
- Assessment of right ventricular sympathetic dysfunction in patients with arrhythmogenic right ventricular cardiomyopathy: AnJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- How do we establish cardiac sympathetic nervous system imaging withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Iodine-123-metaiodobenzylguanidine cardiac SPECT imaging in the qualification of heart failure patients for ICD implantation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Phase dyssynchrony andJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Prediction of sudden cardiac death in patients with chronic heart failure by regional washout rate in cardiac MIBG SPECT imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Development of anAsia Oceania journal of nuclear medicine & biology · 2018Article
- Cross calibration ofAnnals of nuclear medicine · 2017Article
- Standardization ofClinical and translational imaging · 2017Review
- Uptake Index ofAsia Oceania journal of nuclear medicine & biology · 2017Article
- Quantitative iodine-123-metaiodobenzylguanidine (MIBG) SPECT imaging in heart failure with left ventricular systolic dysfunction: Development and validation of automated procedures in conjunction with technetium-99m tetrofosmin myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- ASNC imaging guidelines for SPECT nuclear cardiology procedures: Stress, protocols, and tracers.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Relationship of promising methods in the detection of anthracycline-induced cardiotoxicity in breast cancer patients.Cancer chemotherapy and pharmacology · 2015Article
- Quantification of I-123-meta-iodobenzylguanidine heart-to-mediastinum ratios: not so simple after all.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate global quantitation of cardiac uptake on I-123 mIBG SPECT.
methodsThe study included a pilot group of 67 subjects and a validation group of 1,051 subjects. SPECT images were reconstructed by filtered backprojection, ordered subsets expectation maximization, and deconvolution of septal penetration, respectively. SPECT heart-to-mediastinum ratio (H/M) was calculated by comparing the mean counts between heart and mediastinum volumes of interest drawn on transaxial images. Receiver operating characteristic (ROC) analysis was used to assess the capability of each SPECT method to differentiate the heart disease subjects from controls in comparison with that of the planar H/M.
resultsIn the validation group, the areas under the ROC curves were not significantly different between the SPECT and planar H/M. Order subsets expectation maximization had significantly larger area under the ROC curve than the other two SPECT methods.
conclusionH/M obtained from I-123 mIBG SPECT was equivalent to the planar H/M for differentiating between subjects with normal and abnormal mIBG uptake. Global quantification of cardiac I-123 mIBG SPECT may represent a viable alternative to the planar H/M.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.