Evidence map›Paper›PMID 22147345›Full record

ArticlePediatric blood & cancer2012

Isochromosome 17q, MYC amplification and large cell/anaplastic phenotype in a case of medullomyoblastoma with extracranial metastases.

Karen D Wright, Kendra von der Embse, Jamie Coleman, Zoltan Patay, David W Ellison, Amar Gajjar

Abstract readCase Reports
In one paragraph

Article in Pediatric blood & cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Medulloblastoma.Journal of child neurology · 2016
    Review
  2. Article
  3. Isochromosome 17q in Chronic Lymphocytic Leukemia.Leukemia research and treatment · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karen D WrightDepartment of Oncology, Division of Neuro-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-3678, USA. karen.wright@stjude.org
Kendra von der Embse
Jamie Coleman
Zoltan Patay
David W Ellison
Amar Gajjar
St. Jude Children's Research Hospital · USOhio University · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
PROFESSIONAL ONCOLOGY EDUCATION PROGRAMR25CA023944 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI SUZANNE A. GRONEMEYER · 1986 to 2026
$8.3M
NCI NIH HHS P30 CA021765NCI NIH HHS P30 CA21765NCI NIH HHS R25 CA023944
6 · The paper itself

Abstract

Medullomyoblastoma (MMB) is a rare variant of medulloblastoma, a member of the family of central nervous system (CNS) embryonal tumors. The outcome of standard therapy for CNS embryonal tumors is often unpredictable in the setting of MMB. Here, we present the clinical course and treatment of an almost 4-year-old girl with MMB that was characterized by MYC amplification, isochromosome 17q and large cell/anaplastic histopathology.

Indexed as

Chromosomes, Human, Pair 17Gene AmplificationGenes, mycIsochromosomesCerebellar NeoplasmsChild, PreschoolFemaleHumansMedulloblastomaNeoplasm MetastasisPrognosis

Identifiers

PMID22147345
PMCPMC3392450
OpenAlexW2152914979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.