ArticleJournal of neurology2012
Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor.
Article in Journal of neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Semi-quantitative data on ethanol consumption in 354 ET cases and 370 controls.Journal of the neurological sciences · 2014Article
- Substance of abuse and movement disorders: complex interactions and comorbidities.Current drug abuse reviews · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethanol is known to improve tremor in a proportion of patients with essential tremor. Increased incidence of alcoholism has been suspected in essential tremor patients; however, no objective evaluation has been performed using laboratory markers to date. Data on alcohol intake in the last 30 days were acquired in 95 essential tremor patients and 35 healthy controls. Blood and urine markers related to alcohol metabolism and liver function were evaluated. Self-reported alcohol intake and biomarker levels were higher in essential tremor, but the difference was only significant for carbohydrate-deficient transferrin. None of the subjects presented with laboratory parameters reflecting chronic alcohol abuse. Our data do not reflect a higher incidence of alcoholism in patients with essential tremor. Their alcohol intake is well controlled and does not exceed the limits of healthy social drinking.
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Registered trials
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