ArticleInternational journal of colorectal disease2012
Analysis of the seventh edition of American Joint Committee on colon cancer staging.
Article in International journal of colorectal disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bevacizumab Combined with Chemotherapy Improves Survival for Patients with Metastatic Colorectal Cancer: Evidence from Meta Analysis.PloS one · 2016Pooled it
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- Dickkopf 4 Alone and in Combination with Leucyl-tRNA Synthetase as a Good Prognostic Biomarker for Human Colorectal Cancer.BioMed research international · 2023Article
- An Analysis of the Gene Expression Associated with Lymph Node Metastasis in Colorectal Cancer.International journal of genomics · 2023Article
- Identifying the critical state of complex biological systems by the directed-network rank score method.Bioinformatics (Oxford, England) · 2022Article
- Chemotherapy exacerbates the survival paradox of colon cancer: a propensity score matching analysis.Translational cancer research · 2022Article
- CaMKII Mediates TGFβ1-Induced Fibroblasts Activation and Its Cross Talk with Colon Cancer Cells.Digestive diseases and sciences · 2022Article
- Survival Contradiction in Stage II, IIIA, And IIIB Colon Cancer: A Surveillance, Epidemiology, and End Result-Based Analysis.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Stage II colon cancer staging using the number of retrieved lymph nodes may be superior to current TNM staging for prognosis stratification: the Japanese study group for postoperative follow-up of colorectal cancer.International journal of colorectal disease · 2021Article
- Comparison of Long-Term Survival Outcomes of T4a and T4b Colorectal Cancer.Frontiers in oncology · 2021Article
- Prognostic value of CXCL17 and CXCR8 expression in patients with colon cancer.Oncology letters · 2020Article
- MicroRNA-196b-5p promotes malignant progression of colorectal cancer by targeting ING5.Cancer cell international · 2020Article
- Cancer stem cell associated eight gene-based signature predicts clinical outcomes of colorectal cancer.Oncology letters · 2019Article
- Article
- miR-410 acts as an oncogene in colorectal cancer cells by targeting dickkopf-related protein 1 via the Wnt/β-catenin signaling pathway.Oncology letters · 2019Article
- Stage II-III colon cancer: a comparison of survival calculators.Journal of gastrointestinal oncology · 2018Article
- miR-888 functions as an oncogene and predicts poor prognosis in colorectal cancer.Oncology letters · 2018Article
- Long noncoding RNA DANCR promotes colorectal cancer proliferation and metastasis via miR-577 sponging.Experimental & molecular medicine · 2018Article
- Survival Contradiction Between Stage IIA and Stage IIIA Rectal Cancer: A Retrospective Study.Journal of Cancer · 2018Article
- miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA.Cancer management and research · 2018Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe seventh edition of the American Joint Committee on Cancer (AJCC) staging system has new substages for colon cancer. We used survival data from a single medical center to analyze this new AJCC edition.
methodsThe colon cancer database of Taipei Veterans General Hospital provided 1,865 patient records covering from 1999 to 2005. Survival rates were evaluated using the Kaplan-Meier method.
resultsThere were 268, 607, 561, and 421 patients in stages I, II, III, and IV disease with 5-year observed survival rates of 86.3%, 79.2%, 65.4%, and 12.8%, respectively. Survival rates were not significantly different between those with T4a and T4b disease (P = 0.806). The outcome of N1c disease was similar to N1a and N1b but worse than N0 (P = 0.004). Survival rates for M1a and M1b disease became different after reclassifying solely peritoneal seeding as M1a (P < 0.001). No discrepancy of outcomes between stage IIIA and stage IIB/IIC remained in the seventh edition.
conclusionsEvolution from the fifth to seventh edition of the AJCC staging system is successful in separating prognostic groups by substaging. But some issues remain unresolved, including the subdivision of T4, N1, and M1.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.