ReviewCritical care (London, England)2011
Year in review 2010: Critical Care--Multiple organ dysfunction and sepsis.
Review in Critical care (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data.Mediators of inflammation · 2015Pooled it
- Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis.Cytokine · 2016Trial
- Factors Associated With Initiation of Mechanical Ventilation in Patients With Sepsis: Retrospective Observational Study.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2023Observational
- Gene expression profiling of sepsis-associated acute kidney injury.Experimental and therapeutic medicine · 2020Article
- [Procalcitonin as a tool for the assessment of successful therapy of severe sepsis : An analysis using clinical routine data].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2018Review
- Acute Inflammation and Metabolism.Inflammation · 2018Review
- Unveiling differentially expressed genes upon regulation of transcription factors in sepsis.3 Biotech · 2017Article
- Article
- Diagnostic and Predictive Levels of Calcium-binding Protein A8 and Tumor Necrosis Factor Receptor-associated Factor 6 in Sepsis-associated Encephalopathy: A Prospective Observational Study.Chinese medical journal · 2016Observational
- Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis.Intensive care medicine experimental · 2015Article
- Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis.Critical care (London, England) · 2015Article
- In silico modeling: methods and applications to trauma and sepsis.Critical care medicine · 2013Review
- Peroxisome proliferator-activated receptor-γ activation prevents sepsis-related cardiac dysfunction and mortality in mice.Circulation. Heart failure · 2013Article
- Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury.Signal transduction and targeted therapyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review summarizes new insights in the pathophysiologic implications of inflammation and microvascular alterations in organ dysfunction, as well as genetic factor contribution, from clinical and experimental studies that were published in 2010 in Critical Care in the fields of multiple organ dysfunction and sepsis. New diagnostic and prognostic markers of organ dysfunction are presented. Evaluations of novel therapeutic strategies, including implementation of international guidelines, modulation of inflammation and coagulation, and prevention of ventilator-induced lung injury and acute kidney injury, are reported. The results of these experimental studies and clinical trials are discussed in the context of the current relevant scientific and clinical background.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.