ArticleMolecular plant pathology2012
Transcriptome analysis of Stagonospora nodorum: gene models, effectors, metabolism and pantothenate dispensability.
Article in Molecular plant pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Exploring rare coumarins biosynthesis by Gloeophyllum trabeum: an integrated computational genomics, molecular docking and spectroscopic approach.World journal of microbiology & biotechnology · 2026Article
- Heterologous expression of anChemical science · 2025Article
- Repeat-induced point mutations driving Parastagonospora nodorum genomic diversity are balanced by selection against non-synonymous mutations.Communications biology · 2024Article
- Regulatory insight for a Zn2Cys6 transcription factor controlling effector-mediated virulence in a fungal pathogen of wheat.PLoS pathogens · 2024Article
- The Velvet transcription factor PnVeA regulates necrotrophic effectors and secondary metabolism in the wheat pathogen Parastagonospora nodorum.BMC microbiology · 2024Article
- Article
- What lies behind the large genome ofFrontiers in fungal biology · 2024Article
- Review
- Article
- Volatile Molecules Secreted by the Wheat PathogenFrontiers in microbiology · 2020Article
- A specific fungal transcription factor controls effector gene expression and orchestrates the establishment of the necrotrophic pathogen lifestyle on wheat.Scientific reports · 2019Article
- Active Fungal Communities in AsymptomaticMicroorganisms · 2019Article
- Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system.Chemical science · 2019Article
- Pan-Parastagonospora Comparative Genome Analysis-Effector Prediction and Genome Evolution.Genome biology and evolution · 2018Article
- A Review of the Interactions between Wheat and Wheat Pathogens: Zymoseptoria tritici, Fusarium spp. and Parastagonospora nodorum.International journal of molecular sciences · 2018Review
- A fungal wheat pathogen evolved host specialization by extensive chromosomal rearrangements.The ISME journal · 2017Article
- Differential effector gene expression underpins epistasis in a plant fungal disease.The Plant journal : for cell and molecular biology · 2016Article
- Article
- SnPKS19 Encodes the Polyketide Synthase for Alternariol Mycotoxin Biosynthesis in the Wheat Pathogen Parastagonospora nodorum.Applied and environmental microbiology · 2015Article
- An in planta-expressed polyketide synthase produces (R)-mellein in the wheat pathogen Parastagonospora nodorum.Applied and environmental microbiology · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The wheat pathogen Stagonospora nodorum, causal organism of the wheat disease Stagonospora nodorum blotch, has emerged as a model for the Dothideomycetes, a large fungal taxon that includes many important plant pathogens. The initial annotation of the genome assembly included 16,586 nuclear gene models. These gene models were used to design a microarray that has been interrogated with labelled transcripts from six cDNA samples: four from infected wheat plants at time points spanning early infection to sporulation, and two time points taken from growth in artificial media. Positive signals of expression were obtained for 12,281 genes. This represents strong corroborative evidence of the validity of these gene models. Significantly differential expression between the various time points was observed. When infected samples were compared with axenic cultures, 2882 genes were expressed at a higher level in planta and 3630 were expressed more highly in vitro. Similar numbers were differentially expressed between different developmental stages. The earliest time points in planta were particularly enriched in differentially expressed genes. A disproportionate number of the early expressed gene products were predicted to be secreted, but otherwise had no obvious sequence homology to functionally characterized genes. These genes are candidate necrotrophic effectors. We have focused attention on genes for carbohydrate metabolism and the specific biosynthetic pathways active during growth in planta. The analysis points to a very dynamic adjustment of metabolism during infection. Functional analysis of a gene in the coenzyme A biosynthetic pathway showed that the enzyme was dispensable for growth, indicating that a precursor is supplied by the plant.
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