Evidence map›Paper›PMID 22145139›Full record

ArticleIndian journal of endocrinology and metabolism2011

The thyroid hormone, parathyroid hormone and vitamin D associated hypertension.

Sandeep Chopra, Davis Cherian, Jubbin J Jacob

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Vitamin D-Parathyroid Hormone-Fibroblast Growth Factor 23 Axis and Cardiac Remodeling.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Association of thyroid function with white coat hypertension and sustained hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Observational
  7. Article
  8. Atherosclerotic Surrogate Markers in Adults With Down Syndrome: A Case-Control Study.Journal of clinical hypertension (Greenwich, Conn.) · 2017
    Article
  9. Article
  10. Noninvasive indicators of atherosclerosis in subclinical hypothyroidism.Indian journal of endocrinology and metabolism · 2013
    Article
  11. Relationship of Vitamin D Status with Thyroid Autoimmunity in New Onset Autoimmune Hypothyroidism.Nigerian medical journal : journal of the Nigeria Medical Association
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sandeep ChopraDepartment of Cardiology, Christian Medical College, Ludhiana, India.
Davis Cherian
Jubbin J Jacob
Christian Medical College · INChristian Medical College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid disorders and primary hyperparathyroidism have been known to be associated with increases in blood pressure. The hypertension related to hypothyroidism is a result of increased peripheral resistance, changes in renal hemodynamics, hormonal changes and obesity. Treatment of hypothyroidism with levo-thyroxine replacement causes a decrease in blood pressure and an overall decline in cardiovascular risk. High blood pressure has also been noted in patients with subclinical hypothyroidism. Hyperthyroidism, on the other hand, is associated with systolic hypertension resulting from an expansion of the circulating blood volume and increase in stroke volume. Increased serum calcium levels associated with a primary increase in parathyroid hormone levels have been also associated with high blood pressure recordings. The mechanism for this is not clear but the theories include an increase in the activity of the renin-angiotensin-aldosterone system and vasoconstriction. Treatment of primary hyperparathyroidism by surgery results in a decline in blood pressure and a decrease in the plasma renin activity. Finally, this review also looks at more recent evidence linking hypovitaminosis D with cardiovascular risk factors, particularly hypertension, and the postulated mechanisms linking the two.

Indexed as

Hypertensionhyperthyroidismhypothyroidismprimary hyperparathyroidismvitamin D

Identifiers

PMID22145139
PMCPMC3230087
OpenAlexW2024571178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.