ArticleThe American journal of tropical medicine and hygiene2011
Long-term albendazole effectiveness for hepatic cystic echinococcosis.
Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Medical treatment of cystic echinococcosis: systematic review and meta-analysis.BMC infectious diseases · 2018Pooled it
- A study of hepatic hydatid cysts, focusing on cystobiliary fistula formation in children.Pediatric surgery international · 2025Article
- Assessment of compliance and therapeutic efficacy of albendazole treatment in Chinese patients with echinococcosis.Infectious diseases of poverty · 2024Article
- Follow up study of symptomatic human cystic echinococcosis treatment with albendazole and praziquantel, in Uruguay.BMC infectious diseases · 2024Article
- Treatment of hepatic and pulmonary hydatidosis with albendazole and praziquantel.Helminthologia · 2023Article
- Unusual case of disappearing hepatic hydatid cyst: COVID-19 times.BMJ case reports · 2021Article
- A case for adoption of continuous albendazole treatment regimen for human echinococcal infections.PLoS neglected tropical diseases · 2020Article
- Study on the effect of an ion channel inhibitor "Fluralaner" onJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2020Article
- Progress in the pharmacological treatment of human cystic and alveolar echinococcosis: Compounds and therapeutic targets.PLoS neglected tropical diseases · 2018Article
- Patent landscape of neglected tropical diseases: an analysis of worldwide patent families.Globalization and health · 2017Article
- Cystic echinococcosis of the liver: A primer for hepatologists.World journal of hepatology · 2014Review
- Echinococcus granulosus genomics: a new dawn for improved diagnosis, treatment, and control of echinococcosis.Parasite (Paris, France) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little is known about the long-term effectiveness of albendazole in the medical therapy of non-complicated hepatic cystic echinococcosis (HCE) in resource-constrained settings. We performed a retrospective review of patients starting albendazole for HCE in Lima, Peru from January 1997 to December 2007. Patients successfully recontacted underwent chart abstraction and clinical and ultrasonographic reevaluation. Descriptive statistics were used to delineate patient characteristics and treatment effectiveness at the conclusion of albendazole and after reevaluation. Patients (N = 27) were primarily female, mean age was 51. Initial treatment success at albendazole conclusion was 26% (N = 7) per patient and 37.5% (N = 24) per cyst. After 3.8 ± 2.5 years, albendazole success was 34% (N = 9) per patient and 40% (N = 24) per cyst. We found a gap in the effectiveness of albendazole HCE therapy compared with the efficacy reported in clinical trials. This underscores the need for further investigation into alternate therapeutic strategies for this neglected disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.