ArticleMagnetic resonance in medicine2012
The magnetic field dependence of water T1 in tissues.
Article in Magnetic resonance in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Longitudinal relaxation rate (Magma (New York, N.Y.) · 2025Pooled it
- Quantitative MRI to Assess Portal Pressure in Patients With Liver Disease: Validation at 3 T.NMR in biomedicine · 2026Article
- Heptanuclear iron complex as a potential contrast agent for MRI.Magnetic resonance letters · 2026Article
- Article
- Water Dynamics in Fish Collagen Gels-Insight from NMR Relaxometry.Materials (Basel, Switzerland) · 2024Article
- Double pulsed field gradient diffusion MRI to assess skeletal muscle microstructure.Magnetic resonance in medicine · 2023Article
- Survey of water proton longitudinal relaxation in liver in vivo.Magma (New York, N.Y.) · 2021Review
- Varying diffusion time to discriminate between simulated skeletal muscle injury models using stimulated echo diffusion tensor imaging.Magnetic resonance in medicine · 2021Article
- Intracellular Water Lifetime as a Tumor Biomarker to Monitor Doxorubicin TreatmentFrontiers in oncology · 2021Article
- Low-field and variable-field NMR relaxation studies of H2O and D2O molecular dynamics in articular cartilage.PloS one · 2021Article
- Towards applying NMR relaxometry as a diagnostic tool for bone and soft tissue sarcomas: a pilot study.Scientific reports · 2020Article
- BNeuroImage · 2020Article
- A whole-body Fast Field-Cycling scanner for clinical molecular imaging studies.Scientific reports · 2019Article
- Ion-specificity and surface water dynamics in protein solutions.Physical chemistry chemical physics : PCCP · 2018Article
- Relationships between tissue microstructure and the diffusion tensor in simulated skeletal muscle.Magnetic resonance in medicine · 2018Article
- Evidence for the Role of Intracellular Water Lifetime as a Tumour Biomarker Obtained by In Vivo Field-Cycling Relaxometry.Angewandte Chemie (International ed. in English) · 2018Article
- Ultra-wide range field-dependent measurements of the relaxivity of GdScientific reports · 2017Article
- Numerical evaluation of image homogeneity, signal-to-noise ratio, and specific absorption rate for human brain imaging at 1.5, 3, 7, 10.5, and 14T in an 8-channel transmit/receive array.Journal of magnetic resonance imaging : JMRI · 2015Article
- Eddy current compensation for delta relaxation enhanced MR by dynamic reference phase modulation.Magma (New York, N.Y.) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The magnetic field dependence of the composite (1)H(2)O nuclear magnetic resonance signal T(1) was measured for excised samples of rat liver, muscle, and kidney over the field range from 0.7 to 7 T (35-300 MHz) with a nuclear magnetic resonance spectrometer using sample-shuttle methods. Based on extensive measurements on simpler component systems, the magnetic field dependence of T(1) of all tissues studied are readily fitted at Larmor frequencies above 1 MHz with a simple relaxation equation consisting of three contributions: a power law, A*ω(-0.60) related to the interaction of water with long-lived-protein binding sites, a logarithmic term B*τ(d) *log(1+1/(ωτ(d))(2)) related to water diffusion at macromolecular interfacial regions, and a constant term associated with the high frequency limit of water-spin-lattice relaxation. The parameters A and B include the concentration and surface area dependences respectively. The logarithmic diffusion term becomes significant at high magnetic fields and is consistent with rapid translational dynamics at macromolecular surfaces. The data are fitted well with translational correlation times of approximately 15 ps for human brain white matter, but with a B value three times larger than gray matter tissues. This analysis suggests that the water-surface translational correlation time is approximately three times longer than in gray matter.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.