ArticleMethods in molecular biology (Clifton, N.J.)2012
Isolation of undifferentiated and early differentiating type A spermatogonia from Pou5f1-GFP reporter mice.
Article in Methods in molecular biology (Clifton, N.J.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Primordial germ cell-like cells residing in the pituitary may serve as the origin of intracranial germ cell tumors.Scientific reports · 2026Article
- scATAC-Seq reveals heterogeneity associated with spermatogonial differentiation in cultured male germline stem cells.Scientific reports · 2022Article
- A novel approach to nonsurgical sterilization; application of menadione-modified gonocyte-targeting M13 bacteriophage for germ cell ablation in utero.Pharmacology research & perspectives · 2020Article
- Article
- BRG1 Is Dispensable for Sertoli Cell Development and Functions in Mice.International journal of molecular sciences · 2020Article
- Spermatogonial Stem Cells in Fish: Characterization, Isolation, Enrichment, and Recent Advances of In Vitro Culture Systems.Biomolecules · 2020Review
- Unified single-cell analysis of testis gene regulation and pathology in five mouse strains.eLife · 2019Article
- Advanced immunostaining approaches to study early male germ cell development.Stem cell research · 2018Article
- The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells.Stem cells and development · 2017Article
- Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice.Reproduction (Cambridge, England) · 2016Article
- Advances in Isolation Methods for Spermatogonial Stem Cells.Stem cell reviews and reports · 2016Review
- The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis.Cell reports · 2015Article
- Reporter mice express green fluorescent protein at initiation of meiosis in spermatocytes.Genesis (New York, N.Y. : 2000) · 2014Article
- RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche.Development (Cambridge, England) · 2014Article
- Transient acid treatment cannot induce neonatal somatic cells to become pluripotent stem cells.F1000Research · 2014Article
- Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence.Developmental biology · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Limited understanding of the mechanisms underlying self-renewal and differentiation of spermatogonial stem cells hampers our ability to develop new therapeutic and contraceptive approaches. Mouse models of spermatogonial stem cell development are key to developing new insights into the biology of both the normal and diseased testis. Advances in transgenic reporter mice have enabled the isolation, molecular characterization, and functional analysis of mouse Type A spermatogonia subpopulations from the normal testis, including populations enriched for spermatogonial stem cells. Application of these reporters both to the normal testis and to gene-deficient and over-expression models will promote a better understanding of the earliest steps of spermatogenesis, and the role of spermatogonial stem cells in germ cell tumor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.