ArticleGenetics2012
Scrambling eggs: meiotic drive and the evolution of female recombination rates.
Article in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
59 citing papers in PubMed, 111 citations in OpenAlex.
- A comparative study on recombination activity in cattle.Genetics, selection, evolution : GSE · 2026Article
- Sex differences in crossover interference in house mice.G3 (Bethesda, Md.) · 2026Article
- Article
- Meiotic Recombination in Teleosts.Advances in experimental medicine and biology · 2026Review
- Sex differences in crossover interference in house mice.bioRxiv : the preprint server for biology · 2025Article
- Comparative Phylogenetics Reveal Clade-specific Drivers of Recombination Rate Evolution Across Vertebrates.Molecular biology and evolution · 2025Article
- A selfish supergene causes meiotic drive through both sexes inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Estimating realized relatedness in free-ranging macaques by inferring identity-by-descent segments.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Diversification and recurrent adaptation of the synaptonemal complex in Drosophila.PLoS genetics · 2025Article
- Chromosome-level genome assemblies and genetic maps reveal heterochiasmy and macrosynteny in endangered Atlantic Acropora.BMC genomics · 2024Article
- A high-density linkage map reveals broad- and fine-scale sex differences in recombination in the hihi (stitchbird; Notiomystis cincta).Heredity · 2024Article
- The Genetic Architecture of Recombination Rates is Polygenic and Differs Between the Sexes in Wild House Sparrows (Passer domesticus).Molecular biology and evolution · 2024Article
- Fine-scale contemporary recombination variation and its fitness consequences in adaptively diverging stickleback fish.Nature ecology & evolution · 2024Article
- A high-density linkage map and sex-determination loci in Pacific white shrimp (Litopenaeus vannamei).BMC genomics · 2024Article
- Taking identity-by-descent analysis into the wild: Estimating realized relatedness in free-ranging macaques.bioRxiv : the preprint server for biology · 2024Article
- Modeling Recombination Rate as a Quantitative Trait Reveals New Insight into Selection in Humans.Genome biology and evolution · 2023Article
- High-resolution mapping reveals hotspots and sex-biased recombination in Populus trichocarpa.G3 (Bethesda, Md.) · 2023Article
- New insights into Xenopus sex chromosome genomics from the Marsabit clawed frog X. borealis.Journal of evolutionary biology · 2022Article
- Recombination rates in pigs differ between breeds, sexes and individuals, and are associated with the RNF212, SYCP2, PRDM7, MEI1 and MSH4 loci.Genetics, selection, evolution : GSE · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of sex and recombination, the widespread pattern of sex differences in the recombination rate is not well understood and has received relatively little theoretical attention. Here, we argue that female meiotic drivers--alleles that increase in frequency by exploiting the asymmetric cell division of oogenesis--present a potent selective pressure favoring the modification of the female recombination rate. Because recombination plays a central role in shaping patterns of variation within and among dyads, modifiers of the female recombination rate can function as potent suppressors or enhancers of female meiotic drive. We show that when female recombination modifiers are unlinked to female drivers, recombination modifiers that suppress harmful female drive can spread. By contrast, a recombination modifier tightly linked to a driver can increase in frequency by enhancing female drive. Our results predict that rapidly evolving female recombination rates, particularly around centromeres, should be a common outcome of meiotic drive. We discuss how selection to modify the efficacy of meiotic drive may contribute to commonly observed patterns of sex differences in recombination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.